Introduction
Introduction, The Introduction, Intro, or The Intro may refer to:
- Foreword, a beginning section of a book, before the introduction, usually written by someone other than the author
Intro (R&B group)
Intro is an American R&B trio from Brooklyn, New York City, New York. The trio consisted of members Jeff Sanders, Clinton "Buddy" Wike and lead singer/songwriter Kenny Greene. Intro released two albums (for Atlantic Records): 1993's Intro and their second album, 1995's New Life. The group had a string of US hits in the 1990s. The hits included the singles "Let Me Be The One", the Stevie Wonder cover "Ribbon in the Sky", "Funny How Time Flies" and their highest charting hit, "Come Inside".
Intro's Kenny Greene died from complications of AIDS in 2001. Intro recently emerged as a quintet consisting of Clinton "Buddy" Wike, Jeff Sanders, Ramon Adams and Eric Pruitt. Adams departed in 2014, with the group back down to its lineup as a trio. They are currently recording a new album to be released in 2015. The group released a new single in 2013 called "I Didn't Sleep With Her" and a new single "Lucky" in October 2014.
Discography
Albums
Singles
References
Introduction (music)
In music, the introduction is a passage or section which opens a movement or a separate piece, preceding the theme or lyrics. In popular music this is often abbreviated as intro. The introduction establishes melodic, harmonic, and/or rhythmic material related to the main body of a piece.
Introductions may consist of an ostinato that is used in the following music, an important chord or progression that establishes the tonality and groove for the following music, or they may be important but disguised or out-of-context motivic or thematic material. As such the introduction may be the first statement of primary or other important material, may be related to but different from the primary or other important material, or may bear little relation to any other material.
A common introduction to a rubato ballad is a dominant seventh chord with fermata,
Play an introduction that works for many songs is the last four or eight measures of the song, Play while a common introduction to the twelve-bar blues is a single chorus. Play
Wizard (character class)
The Wizard is a type of magical character class in certain role-playing games, including role-playing video games. Wizards are considered to be spellcasters who wield powerful spells, but are often physically weak as a trade-off. Wizards are commonly confused with similar offensive spellcasting classes such as the Warlock and the Necromancer. However, a Wizard's power is based on the arcane and a Warlock or Necromancer's power is based on darkness or death. Wizards are primarily based on wizards from assorted fantasy literature. Other terms used to describe the classification include Mage, Magician, and Magic User.
Dungeons & Dragons
The Dungeons & Dragons pen-and-paper franchise has three base character classes, with access to "arcane magic", that could be considered wizards:
Wizard
The wizard is a "genius student" of arcane magic, who has studied the subject for years. He practices until he is able to command magic with ease. The wizard must prepare spells daily. They are normally called 'magic-users'.
Mage (comics)
Mage is an American superhero comic book written and illustrated by Matt Wagner. Three volumes, each of 15 issues are planned; as of 2014, two have been published.
Publication history
Volume one, The Hero Discovered, was published by Comico from February 1984 to December 1986. Despite advertisements saying that a sequel was "coming soon", The Hero Defined did not appear until 1997, published by Image Comics (Comico had gone bankrupt in 1990, and it had taken some time for Wagner to regain the rights to the series). The third and final volume, The Hero Denied, is planned, but no firm publication schedule fixed.
Wagner wrote and drew both series, with Sam Kieth as inker for part of the first, and Jeromy Cox as colourist for the second.
Plot synopsis
The Hero Discovered follows Kevin Matchstick, an alienated young man who meets a wizard called Mirth and discovers that he, among other things, possesses both a magic baseball bat and superhuman abilities. In the course of the comic, he defeats the nefarious plans of a being called the Umbra Sprite. He ultimately discovers that Mirth is Merlin, the baseball bat is Excalibur, and he is, in some ambiguous way, King Arthur. All the chapter titles are lines from Shakespeare's Hamlet.
MAGEA3
Melanoma-associated antigen 3 (MAGE-A3) is a protein that in humans is encoded by the MAGEA3 gene.
Genetics
This gene is a member of the melanoma-associated antigen gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
Function and Clinical relevance
The normal function of MAGE-A3 in healthy cells is unknown. The presence of the antigen on tumor cells has been associated with worse prognosis. In one study, high levels of MAGE-A3 in lung adenocarcinoma were associated with shorter survival.
MAGE-A3 is a tumor-specific protein, and has been identified on many tumors including melanoma, non-small cell lung cancer, hematologic malignancies, among others. Currently, GlaxoSmithKline is developing a cancer vaccine targeting MAGE-A3. The vaccine is a fusion protein of MAGE-A3 and Haemophilus influenzae protein D, combined with a proprietary immunoadjuvant.
