Introduction

Introduction, The Introduction, Intro, or The Intro may refer to:

Intro (R&B group)

Intro is an American R&B trio from Brooklyn, New York City, New York. The trio consisted of members Jeff Sanders, Clinton "Buddy" Wike and lead singer/songwriter Kenny Greene. Intro released two albums (for Atlantic Records): 1993's Intro and their second album, 1995's New Life. The group had a string of US hits in the 1990s. The hits included the singles "Let Me Be The One", the Stevie Wonder cover "Ribbon in the Sky", "Funny How Time Flies" and their highest charting hit, "Come Inside".

Intro's Kenny Greene died from complications of AIDS in 2001. Intro recently emerged as a quintet consisting of Clinton "Buddy" Wike, Jeff Sanders, Ramon Adams and Eric Pruitt. Adams departed in 2014, with the group back down to its lineup as a trio. They are currently recording a new album to be released in 2015. The group released a new single in 2013 called "I Didn't Sleep With Her" and a new single "Lucky" in October 2014.

Discography

Albums

Singles

References

Introduction (music)

In music, the introduction is a passage or section which opens a movement or a separate piece, preceding the theme or lyrics. In popular music this is often abbreviated as intro. The introduction establishes melodic, harmonic, and/or rhythmic material related to the main body of a piece.

Introductions may consist of an ostinato that is used in the following music, an important chord or progression that establishes the tonality and groove for the following music, or they may be important but disguised or out-of-context motivic or thematic material. As such the introduction may be the first statement of primary or other important material, may be related to but different from the primary or other important material, or may bear little relation to any other material.

A common introduction to a rubato ballad is a dominant seventh chord with fermata, Play  an introduction that works for many songs is the last four or eight measures of the song, Play  while a common introduction to the twelve-bar blues is a single chorus. Play 

Question of fact

In law, a question of fact, also known as a point of fact, is a question which must be answered by reference to facts and evidence, and inferences arising from those facts. Such a question is distinct from a question of law, which must be answered by applying relevant legal principles. The answer to a question of fact (a "finding of fact") is usually dependent on particular circumstances or factual situations.

To illustrate the difference:

After hearing evidence, a U.S. court may issue a "Findings of Fact and Conclusions of Law," which separately examines the factual issues and then draws a legal conclusion. In the above example, the court might write that the facts have been established to a required standard of proof that Mr. and Mrs. Jones left their 10 year old child home alone with a baby for several days. The conclusion of law would then follow, outlining the given child neglect statute that Mr. and Mrs. Jones violated.

Foundation for Art and Creative Technology

FACT (The Foundation for Art & Creative Technology) is a new media arts centre based on Wood Street in Liverpool, England. FACT hosts art projects and exhibitions as well as being a cinema.

History

FACT was Liverpool’s first purpose-built arts centre for more than 60 years. It was opened in February 2003 by its founding executive director Eddie Berg, having cost £10 million to build. The building is linked to Bold Street, one of Liverpool’s main shopping areas, by a public square off Wood Street and Colquitt Street.

The cinema hosted a Question and Answer session with Quentin Tarantino in 2007 for the UK release of Death Proof. After funding cuts in 2014 FACT laid off one quarter of its staff, replacing them with volunteers. In 2015 FACT hosted an art event in which Shia LaBeouf answered phone calls from the public.

The Building

Designed by architectural firm Austin-Smith:Lord, the building is situated on Wood Street in the Ropewalks area of the city centre. It contains three gallery spaces, four cinema screens and a multimedia suite and also comprises a cafe, a bar and a lounge area.

FACT (biology)

FACT (facilitates chromatin transcription) is a heterodimeric protein complex that affects eukaryotic RNA polymerase II (Pol II) transcription elongation both in vitro and in vivo. It was discovered in 1998 as a factor purified from human cells that was essential for productive in vitro Pol II transcription on a chromatinized DNA template.

FACT consists of 140 and 80 kilodalton (kDa) subunits. The 140 kDa subunit is encoded by a human gene (SUPT16H) which is 36% identical to the S. cerevisiae gene Spt16 and the 80 kDa subunit is human SSRP1 (POB3 in S. cerevisiae). Both of these subunits in yeast affect Pol II transcription elongation, and purified human FACT binds specifically to mononucleosomes and the histone H2A/H2B dimer, but not to the H3/H4 tetramer (see: Nucleosome core particle) or Pol II.

Co-immunoprecipitation assays with tagged recombinant proteins showed that the Spt16 subunit interacts with H2A/H2B dimers and mononucleosomes, but not H3/H4 tetramers, whereas the SSRP1 subunit interacts only with H3/H4 tetramers and not mononucleosomes. Deletion of the highly acidic carboxy-terminus of Spt16 (a common feature of known histone chaperones) does not prevent Spt16 from forming a stable complex with SSRP1, but it does eliminate interaction with mononucleosomes and ability to stimulate in vitro transcription on chromatinized templates. The two subunits together, but neither alone, can stimulate formation of nucleosomes from free histones and DNA (histone chaperone activity). These two subunits are highly conserved across all eukaryotes, and in addition to transcription, have been shown to affect DNA repair and replication as well.