Intein
An intein is a segment of a protein that is able to excise itself and join the remaining portions (the exteins) with a peptide bond in a process termed protein splicing. Inteins have also been called "protein introns".
Intein-mediated protein splicing occurs after the intein-containing mRNA has been translated into a protein. This precursor protein contains three segments — an N-extein followed by the intein followed by a C-extein. After splicing has taken place, the resulting protein contains the N-extein linked to the C-extein; this splicing product is also termed an extein.
History
The first intein was discovered in 1988 through sequence comparison between the Neurospora crassa and carrotvacuolar ATPase (without intein) and the homologous gene in yeast (with intein) that was first described as a putative calcium ion transporter. In 1990 Hirata et al. demonstrated that the extra sequence in the yeast gene was transcribed into mRNA and removed itself from the host protein only after translation. Since then, inteins have been found in all three domains of life (eukaryotes, bacteria, and archaea) and in viruses.
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Beautifully Confined
by: EntwineWaking up in these confines (Confines...)
In my thoughs I got my ways to hide it all (to hide it
all...)
Shadows rising, shadows fall
Deep inside I hear them call
I believe I'm done before new dawn
My divide is sleeping filled in my delusions
Strangers we are, still the same as we'd be in love
so bring the morning light and pull the curtains wide
And rise the burning sun
Waking up to realize (Realize...)
Standing out to see the life beyond war
If I'm blinded to collide, in the end I'm crusified
I believe I'm done before new dawn
My divide is sleeping filled in my delusions
Strangers we are, still the the same as we´d be in
love, in the lunar light so pull the curtains tigh
And stands beside me
Strangers we are, still the same as we'd be in love
So bring the morning light and pull the curtains wide
Rise the burning sun
(Solo)
Strangers we are, still the same as we'd be in love
In the lunar light so pull the curtains tight
And stands beside
Strangers we are, still the same as we'd be in love
So bring the morning light and pull the curtains wide