Integrin
Integrins are transmembrane receptors that are the bridges for cell-cell and cell-extracellular matrix (ECM) interactions. When triggered, integrins in turn trigger chemical pathways to the interior (signal transduction), such as the chemical composition and mechanical status of the ECM, which results in a response (activation of transcription) such as regulation of the cell cycle, cell shape, and/or motility; or new receptors being added to the cell membrane. This allows rapid and flexible responses to events at the cell surface, for example to signal platelets to initiate an interaction with coagulation factors.
There are several types of integrins, and a cell may have several types on its surface. Integrins are found in all metazoa.
Integrins work alongside other receptors such as cadherins, the immunoglobulin superfamily cell adhesion molecules, selectins and syndecans to mediate cell–cell and cell–matrix interaction. Ligands for integrins include fibronectin, vitronectin, collagen, and laminin.
Podcasts:
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by North Mississippi Allstars
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by Kelly Joe Phelps
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by Middle Earth
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by Umc's
One To Grow On
by: North Mississippi AllstarsDon’t let ‘em make up your mind for ya
Cause they’re gonna try to run you through the ringer
Before you realize you been hung out to dry
Now, they don’t know that I’m started to learn
You don’t have to be down where the devil stays
For the bottom of your feet to burn
Here’s one to grow on
Too much, never enough
Cold shoulder to cry on
Let your feelings show
Leave some room to grow
Until I go the distance between right and wrong
The road I’ve traveled beyond and long
Too much makes me want to give it all away
Give me something to ease the pain
All washed up, going down the drain
Hung out to dry, left out in the rain
Muster up the courage if I can’t find the strength
I’m gonna shoot like a star on the horizon
When the moon sets the sun rises
Living the life I love, loving the life I live
Really makes me want to away
Loving the life you live, living the life you love
You make the most of everyday
Too much, too much, too much, too much
Too much, never enough
Too much, too much, never enough