Men...

Men… (German: Männer…) is a 1985 West German comedy film directed by Doris Dörrie. It was chosen as West Germany's official submission to the 59th Academy Awards for Best Foreign Language Film, but did not manage to receive a nomination.

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Two and a Half Men

Two and a Half Men is an American television sitcom that began broadcast on CBS on September 22, 2003 and ended on February 19, 2015 after twelve seasons. Originally starring Charlie Sheen, Jon Cryer, and Angus T. Jones, the show was about a hedonistic jingle writer, Charlie Harper; his uptight brother Alan; and Alan's son Jake. After Alan divorces, he moves with his son to share Charlie's beachfront Malibu house and complicate Charlie's freewheeling life.

In 2010, CBS and Warner Bros. Television reached a multi-year broadcast agreement for the series, renewing it through at least the 2011–12 season. But, on February 24, 2011, CBS and Warner Bros. decided to end production for the rest of the eighth season after Sheen entered drug rehabilitation and made "disparaging comments" about the show's creator and executive producer Chuck Lorre. Sheen's contract was terminated on March 7.

The ninth-season premiere, "Nice to Meet You, Walden Schmidt", killed off Sheen's character and introduced Ashton Kutcher as Walden Schmidt, his replacement. Alan is shown moving on with his life after the death of Charlie. He has a new best friend and housemate, Walden, who is dealing with his own troubles following a bad divorce. Walden, Alan, and Jake eventually bond, becoming close friends and forming a surrogate family unit. Jake, who joins the army at the end of season nine, leaves for Japan at the end of season ten.

MEN1

Menin is a protein that in humans is encoded by the MEN1 gene. Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome).

In vitro studies have shown that menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD. However, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Two variants of the shorter transcript have been identified where alternative splicing affects the coding sequence. Five variants where alternative splicing takes place in the 5' UTR have also been identified.

History

In 1988, researchers at Uppsala University Hospital and the Karolinska Institute in Stockholm mapped the MEN1 gene to the long arm of chromosome 11. The gene was finally cloned in 1997.

Genomics

The gene is located on long arm of chromosome 11 (11q13) between base pairs 64,570,985 and 64,578,765. It has 10 exons and encodes a 610-amino acid protein.

Inside (1996 film)

Inside is a 1996 cable television film directed by Arthur Penn based on a script by Bima Stagg. The film was shot in Johannesburg, South Africa and premiered in the USA on Showtime on 25 August 1996. The film was then released theatrically in several markets and played at several film festivals around the world including Cannes, Toronto, San Francisco and Munich. The film was nominated for an Emmy, and a Cable Ace Award.

Plot

Colonel Kruger (Nigel Hawthorne) tortures a political prisoner (Eric Stoltz) to learn who his anti-apartheid collaborators are. Ten years later, this same Colonel himself becomes a prisoner and is interrogated about his own offenses.

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Inside (David Reilly EP)

Inside is the first solo EP released by David Reilly of God Lives Underwater in 2004. "Blaming the Truth" & "Far From Home" are demo versions. Originally appeared on the 'Fluzee 7 EP'. This album was mixed by Jeff Turzo the other half of God Lives Underwater.

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Inside (Paul Horn album)

Inside is a 1968 album by jazz flautist Paul Horn, considered one of the earliest new-age music and world fusion records. The album was recorded inside the Taj Mahal on 25 April 1968, while Horn was with the Beatles in India, and released on the Epic Records label. It has sold over one million copies. The album has been reissued under the name Inside the Taj Mahal.

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? (film)

? (also written Tanda Tanya, meaning Question Mark) is a 2011 Indonesian drama film directed by Hanung Bramantyo. It stars Revalina Sayuthi Temat, Reza Rahadian, Agus Kuncoro, Endhita, Rio Dewanto, and Hengky Sulaeman. The theme is Indonesia's religious pluralism, which often results in conflict between religious beliefs, represented in a plot that revolves around the interactions of three families, one Buddhist, one Muslim, and one Catholic. After undergoing numerous hardships and the deaths of several family members in religious violence, they are reconciled.

Based on Bramantyo's experiences as a mixed-race child, ? was meant to counter the portrayal of Islam as a "radical religion". Owing to the film's theme of religious pluralism and controversial subject matter, Bramantyo had difficulty finding backing. Eventually, Mahaka Pictures put forth Rp 5 billion to fund the production. Filming began on 5 January 2011 in Semarang.

Released on 7 April 2011, ? was a critical and commercial success: it received favourable reviews and was viewed by more than 550,000 people. Also screened internationally, it was nominated for nine Citra Awards at the 2011 Indonesian Film Festival, winning one. However, several Indonesian Muslim groups, including the Indonesian Ulema Council and Islamic Defenders Front, protested against the film because of its pluralist message.