Insanity
Insanity, craziness or madness is a spectrum of behaviors characterized by certain abnormal mental or behavioral patterns. Insanity may manifest as violations of societal norms, including a person becoming a danger to themselves or others, though not all such acts are considered insanity; likewise, not all acts showing indifference toward societal norms are acts of insanity. In modern usage, insanity is most commonly encountered as an informal unscientific term denoting mental instability, or in the narrow legal context of the insanity defense. In the medical profession the term is now avoided in favor of diagnoses of specific mental disorders; the presence of delusions or hallucinations is broadly referred to as psychosis. When discussing mental illness in general terms, "psychopathology" is considered a preferred descriptor.
In English, the word "sane" derives from the Latin adjective sanus meaning "healthy". Juvenal's phrase mens sana in corpore sano is often translated to mean a "healthy mind in a healthy body". From this perspective, insanity can be considered as poor health of the mind, not necessarily of the brain as an organ (although that can affect mental health), but rather refers to defective function of mental processes such as reasoning. Another Latin phrase related to our current concept of sanity is "compos mentis" (lit. "sound of mind"), and a euphemistic term for insanity is "non compos mentis". In law, mens rea means having had criminal intent, or a guilty mind, when the act (actus reus) was committed.
Insane (cancelled video game)
Insane (stylized as inSANE) was a survival horror video game, formerly in development by Volition to be published by THQ, in collaboration with film director Guillermo del Toro. It was being developed for Microsoft Windows, PlayStation 3 and Xbox 360, and was to be released in 2013. It was intended as the first installment of a planned trilogy of Insane video games.
Development
Insane was first announced at the 2010 Spike Video Game Awards on December 11th 2010 by del Toro and Volition, in the form of a thirty-second teaser trailer. Del Toro said of the game, "With this new series of video games, I want to take players to a place they have never seen before, where every single action makes them question their own senses of morality and reality. THQ and Volition, Inc. are equally excited to make this vision of a completely new game universe into a reality."
Comic book artist Guy Davis was one of the key designers of the game. He has previously worked with del Toro on designs for At the Mountains of Madness.
Insane (Texas song)
"Insane" is a song by British band Texas and was the fifth and final single to be released from their fourth studio album White on Blonde. It was released as a double A-side with "Say What You Want (All Day, Every Day)" in 1998. The song was later included on their 2000 compilation album The Greatest Hits.
Track listing
CD1 (MERCD 499)
CD2 (MERDD 499)
Promo CD (MERCJ 499)
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Didanosine
Didanosine (2′,3′-dideoxyinosine, ddI, DDI) marketed under the trade names Videx and Videx EC. It is an antiretroviral medication used to treat HIV/AIDS in combination with other medications as part of highly active antiretroviral therapy (HAART). It is of the reverse transcriptase inhibitor class.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Adverse effects
The most common adverse events with didanosine are diarrhea, nausea, vomiting, abdominal pain, fever, headache and rash. Peripheral neuropathy occurred in 21-26% of participants in key didanosine trials.
Pancreatitis is rarely observed but has caused occasional fatalities, and has black box warning status. Other reported serious adverse events are retinal changes, optic neuritis and alterations of liver functions. The risk of some of these serious adverse events is increased by drinking alcohol.
In February 2010, the United States Food and Drug Administration issued a statement that patients using Didanosine (Videx) are at risk for a rare but potentially fatal liver disorder, non-cirrhotic portal hypertension.
DDI
DDI can be an abbreviation for:
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