Inositol phosphate

Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions, such as cell growth, apoptosis, cell migration, endocytosis, and cell differentiation. The group comprises:

inositol monophosphate (IP)

inositol bisphosphate (IP₂)

inositol trisphosphate (IP₃)

inositol pentakisphosphate (IP₅)

inositol hexaphosphate (IP₆) also known as phytic acid, or phytate (as a salt).

Functions

Inositol triphosphate

Inositol trisphosphates act on the inositol triphosphate receptor to release calcium into the cytoplasm. Further reading: Function of calcium in humans

Other

Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene expression and Steger (both in Science Magazine).

References

↑ Shen, X; Xiao, H; Ranallo, R; Wu, WH; Wu, C (2003). "Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates". Science 299 (5603): 112–4. doi:10.1126/science.1078068. PMID 12434013.

↑ Steger, DJ; Haswell, ES; Miller, AL; Wente, SR; O'Shea, EK (2003). "Regulation of chromatin remodeling by inositol polyphosphates". Science 299 (5603): 114–6. doi:10.1126/science.1078062. PMC 1458531. PMID 12434012.

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Inositol_phosphate

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