In Silico (Deepsky album)

In Silico is a full length artist album by the American electronic music group Deepsky. It was released in 2002. The title refers to the largely computer-based production methods employed during the album's creation, where the bulk of the music was composed using virtual instruments and Emagic Logic Audio 5 rather than external hardware synthesizers and traditional multi-track recorders.

The website AllMusic gave In Silico three stars out of a possible five, with reviewer John Bush stating that the album "has it all: the low attention span of funky breaks, the streamlined groove of progressive trance, even the intelligent production and frequent changeups of techno."

Track listing

In silico

In silico (literally Latin for "in silicon", alluding to the mass use of silicon for semiconductor computer chips) is an expression used to mean "performed on computer or via computer simulation." The phrase was coined in 1989 as an allusion to the Latin phrases in vivo, in vitro, and in situ, which are commonly used in biology (see also systems biology) and refer to experiments done in living organisms, outside of living organisms, and where they are found in nature, respectively.

Drug discovery with virtual screening

In silico study in medicine is thought to have the potential to speed the rate of discovery while reducing the need for expensive lab work and clinical trials. One way to achieve this is by producing and screening drug candidates more effectively. In 2010, for example, using the protein docking algorithm EADock (see Protein-ligand docking), researchers found potential inhibitors to an enzyme associated with cancer activity in silico. Fifty percent of the molecules were later shown to be active inhibitors in vitro. This approach differs from use of expensive high-throughput screening (HTS) robotic labs to physically test thousands of diverse compounds a day often with an expected hit rate on the order of 1% or less with still fewer expected to be real leads following further testing (see drug discovery).

In silico (disambiguation)

In silico is an expression meaning "performed on computer or via computer simulation".

In silico may also refer to:

See also

In Silico (Pendulum album)

In Silico is the second full-length studio album by Australian band Pendulum, released in Australia and Europe on 12 May 2008 by Warner Music UK, and in America on 13 May 2008 by Atlantic. The album represents a change in sound from the band's debut album Hold Your Colour, away from drum and bass, incorporating more rock and electronic influences. The album peaked at number two on the UK Albums Chart on 18 May 2008. Releases from the album include "Granite", "Propane Nightmares", "The Other Side" and "Showdown". Mini discs of the song "The Tempest" were thrown out to the audience of the "Project Rev" live show.

The expression "in silico", from which the album title is derived, is used to mean "performed on computer or via computer simulation", however group member Gareth McGrillen also commented on the way it plays upon Nirvana's well-known album title In Utero (meaning "born naturally" or "of the uterus") and thus carries extra shades of meaning related to being "born synthetically", thus explaining the album's cover motif of a baby or fetus displayed inside a circular design representing a synthetic ovum.