Tropomyosin 4 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | TPM4[] | ||||||||||||
External IDs | OMIM: 600317 MGI: 2449202 HomoloGene: 100849 GeneCards: TPM4 Gene | ||||||||||||
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RNA expression pattern | |||||||||||||
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More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 7171 | 326618 | |||||||||||
Ensembl | ENSG00000167460 | ENSMUSG00000031799 | |||||||||||
UniProt | P67936 | Q6IRU2 | |||||||||||
RefSeq (mRNA) | NM_001145160.1 | NM_001001491 | |||||||||||
RefSeq (protein) | NP_001138632.1 | NP_001001491 | |||||||||||
Location (UCSC) | Chr 19: 16.18 – 16.21 Mb |
Chr 8: 75.06 – 75.08 Mb |
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PubMed search | [1] | [2] | |||||||||||
Tropomyosin alpha-4 chain is a protein that in humans is encoded by the TPM4 gene.[1][2]
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This article on a gene on chromosome 19 is a stub. You can help Wikipedia by expanding it. |
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TPM 21 is a protein found in the human brain. It blocks the neurotoxin abeta, also known as the beta-amyloid peptide, which is responsible for starting alzheimers. This new break through could lead to a treatment of the disorder in the next decade.
"Next" is the second season premiere episode of the American comedy-drama series Desperate Housewives, and the 24th episode overall. It was originally broadcast in the United States on September 25, 2005, on ABC. It was written by Jenna Bans and Kevin Murphy and was directed by Larry Shaw.
In the episode, Susan (Teri Hatcher) recovers from having been held hostage while Gabrielle (Eva Longoria) attempts to salvage her marriage to her incarcerated husband, Carlos (Ricardo Antonio Chavira). Meanwhile, Bree (Marcia Cross) deals with her mother-in-law following her husband's death and Lynette (Felicity Huffman) goes back to work. The episode also introduces the mystery storyline revolving around Betty Applewhite (Alfre Woodard) and her family.
According to Nielsen ratings, "Next" was watched by 28.4 million viewers, making it the most watched season premiere on ABC in nine years. The episode also ranks as the second-most watched in series history, behind the first season finale in May 2005. The episode received general positive reviews, with Cross earning universal praise for her performance. Critics enjoyed Woodward's acting as well as her character's storyline.
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"Swampsnake" was covered by American rock band Zilch on their 1998 debut album 3.2.1..
"The Faith Healer" was covered by Australian psychedelic rock band The Church on their 1999 covers album A Box of Birds.
All songs written and composed by Alex Harvey and Hugh McKenna, except where noted.
Next is a brand of cigarettes made by Altria. The brand was created by Philip Morris International after tax increases of tobacco in Malaysia pushed Marlboro out of the market.Next is also available in tobacco for rolling use.
Next International is sold in Canada as a discount cigarette brand which competes with other imported brands such as Viceroy, Legend, Studio and Pall Mall.