ICI
ICI or Ici may mean:
ICI is also an abbreviation which may mean:
ICI-199,441
ICI-199,441 is a drug which acts as a potent and selective κ-opioid agonist, and has analgesic effects. It is a biased agonist of the KOR, and is one of a relatively few KOR ligands that is G protein-biased rather than β-arrestin-biased.
See also
References
Fulvestrant
Fulvestrant (trade name Faslodex, by AstraZeneca) is a drug treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. It is a complete estrogen receptor antagonist with no agonist effects, which in addition, accelerates the proteasomal degradation of the estrogen receptor. The drug has poor oral bioavailability, and is administered monthly via intramuscular injection.
Clinical uses
Fulvestrant is a selective estrogen receptor degrader (SERD). It is indicated for the treatment of hormone receptor positive metastatic breast cancer in postmenopausal women with disease progression following anti-estrogen therapy. The dosing schedule for fulvestrant remains under investigation in an attempt to optimize its effectiveness.
Clinical trials
Metastatic or locally advanced breast cancer
Fulvestrant provided effective second-line therapy in this setting for postmenopausal women who had relapsed or progressed after previous endocrine therapy.
Podcasts:
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by Tom Petty & The Heartbreakers
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by Anvil
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by Yeah Yeah Yeahs
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by My Ticket Home
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by Babbie Mason
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by Wess Fosso
U.S. 41
by: Tom Petty & The HeartbreakersMy daddy came a-marchin'
Over the hill at dawn
Had to make that wage, man
That's how we got along
My daddy's life was workin'
Workin' all day long
Put food on the table
And the children sang a song
Yes, the children sang a song
My granddad's name was Pulpwood
Wore a coat of green
Took a wife in '31
Drove the big machine
My daddy load the lumber
Put it on the truck
I used to see him walkin' home
On U.S. 41
That's right, U.S. 41
Well, all my life's been workin'
Out the door and gone
Got to make that overtime
Keep us movin' on
I need a drink of water
Get out of the sun
Burnin' up to make that wage
That's right, U.S. 41
The boss man owns the business
Keeps it goin' strong
Blowin' like a hurricane
And work like nothing wrong
We got to keep on movin'
'Til the bell gone ring
Fill her up with kerosene
And let that lady sing
Whoa, now let that lady sing
His given name was Lucky
His wife's name, Annie Brown
Ran outside the law
And they chased him right on down
Lucky faced the lawman
The captain drew his gun
They put him with a sling blade
On U.S. 41
That's right, U.S. 41
Yeah, that's right
On U.S. 41
My daddy came a-marchin'
Over the hill at dawn