Protein IWS1 homolog also known as interacts with Spt6 (IWS1) is a protein that in humans is encoded by the IWS1 gene.
IWS1 an transcription elongation factor. It was first identified during a search for RNA polymerase II-associated elongation factors in yeast; it directly interacts with RNA polymerase II (RNAPII) and is phosphorylated at casein kinase II (CKII) sites. The human homolog, which physically interacts with protein arginine methyltransferase 5 (PRMT5), is essential for cell survival. It also recruits a SET2 histone methyltransferase (Huntingtin-interacting protein HYPB, also known as SETD2) to RNAPII during transcription elongation and is required for H3K36 trimethylation.
I'm tired of my life but my heads alright
I got the fever off a man I know
I can feel it comin' in the air tonight
And I know, I know, I know
Swear I heard a song on the radio
My heart is laughing back at me
I can see it comin' but I just don't know
If it's gon' , it's gon, it's gonna let me be
As I saw, on the breeze
I can see the sons of those who came before me
And it's got me on my knees
What you say, anyway
Will not last, it'll pass, it'll flash right there before me
And it's got me on my knees
Cos I got the fever
Yeah I got the fever
Cos I got the fever
I'm tired of my life but my heads alright
I got the fever off a man I know
I can feel it comin' in the air tonight
And I know, I know, I know
Swear I heard a song on the radio
My heart is laughing back at me
I can see it comin' but I just don't know
If it's gon' , it's gon, it's gonna let me be
As I saw, on the breeze
I can see the sons of those who came before me
And it's got me on my knees
What you say, anyway
Will not last, it'll pass, it'll flash right there before me
And it's got me on my knees
It's got me on my knees
It's got me on my knees
It's got me on my knees
As I saw, on the breeze
I can see the sons of those who came before me
And it's got me on my knees
What you say, anyway
Will not last, it'll pass, it'll flash right there before me
And it's got me on my knees
It's got me on my knees
It's got me on my knees
It's got me on my knees