IUP

IUP may refer to:

IUP (software)

The IUP Portable User Interface is a computer software development kit that provides a portable, scriptable toolkit to build graphical user interfaces (GUIs) using the programming languages C, Perl, Lua and Nim. This allows rapid, zero-compile prototyping and refinement of deployable GUI applications.

IUP's purpose is to allow programs to run in different systems in unmodified form.

It provides this ability by binding Lua with its C/C++ code, or simply writing C to the application programming interface (API). It supports calling native Windows API graphics, native Motif-LessTif or GTK+ elements, or the developers' own CanvasDraw elements from the Lua scripts or natively in a C/C++ application.

Features

IUP's distinguishing features include:

Intrinsically disordered proteins

An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure. IDPs cover a spectrum of states from fully unstructured to partially structured and include random coils, (pre-)molten globules, and large multi-domain proteins connected by flexible linkers. They constitute one of the main types of protein (alongside globular, fibrous and membrane proteins).

The discovery of IDPs has challenged the traditional protein structure paradigm, that protein function depends on a fixed three-dimensional structure. This dogma has been challenged over the last decades by increasing evidence from various branches of structural biology, suggesting that protein dynamics may be highly relevant for such systems. Despite their lack of stable structure, IDPs are a very large and functionally important class of proteins. In some cases, IDPs can adopt a fixed three-dimensional structure after binding to other macromolecules. Overall, IDPs are different from structured proteins in many ways and tend to have distinct properties in terms of function, structure, sequence, interactions, evolution and regulation.