ITS

ITS, its or it's may refer to:

Computing

Entertainment

Organizations

It (pronoun)

"It" /ɪt/ is a third-person, singular neuter pronoun (nominative (subjective) case and oblique (objective) case) in Modern English.

Usage

The word and term 'it' can be used for either a subject or an object in a sentence and can describe any physical or psychological subject and/or object and its genitive form its have been used to refer to human babies and animals, although with the passage of time this usage has come to be considered too impersonal in the case of babies, as it may be thought to demean a conscious being to the status of a mere object. This use of "it" is also criticized when used as a rhetorical device to dehumanize their enemies, implying that they were little more than non-human animals. The word remains in common use however, and its use increases with the degree to which the speaker views an object of speech as impersonal. For example, someone else's dog is often referred to as "it", especially if the dog isn't known by the speaker, or if the dog's gender is unknown. A person would rarely say "it" when referring to his/her own cat or dog. Examples:

Internal transcribed spacer

Internal transcribed spacer (ITS) refers to the spacer DNA situated between the small-subunit ribosomal RNA (rRNA) and large-subunit rRNA genes in the chromosome or the corresponding transcribed region in the polycistronic rRNA precursor transcript. In bacteria and archaea, ITS is located between the 16S and 23S rRNA genes. On the other hand, there are two ITS's in eukaryotes; ITS1 is located between 18S and 5.8S rRNA genes, while ITS2 is between 5.8S and 25S (in plants, or 28S in animals) rRNA genes. ITS1 corresponds to the ITS in bacteria and archaea, while ITS2 originated as an insertion that interrupted the ancestral 23S rRNA gene.

Genes encoding ribosomal RNA and spacers occur in tandem repeats that are thousands of copies long, each separated by regions of non-transcribed DNA termed intergenic spacer (IGS) or non-transcribed spacer (NTS). Sequence comparison of the ITS region is widely used in taxonomy and molecular phylogeny because it a) is easy to amplify even from small quantities of DNA (due to the high copy number of rRNA genes), and b) has a high degree of variation even between closely related species. This can be explained by the relatively low evolutionary pressure acting on such non-functional sequences.