Interleukin-3 receptor
The interleukin-3 receptor (also known as CD123 antigen) is a molecule found on cells which helps transmit the signal of interleukin-3, a soluble cytokine important in the immune system.
The gene coding for the receptor is located in the pseudoautosomal region of the X and Y chromosomes.
The receptor belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CD131) subunit.
The gene for the alpha subunit is 40 kilobases long and has 12 exons.
The receptor, found on pluripotent progenitor cells, induces tyrosine phosphorylation within the cell and promotes proliferation and differentiation within the hematopoietic cell lines.
External links
Podcasts:
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by Train
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by Najwa Nimri
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by Tim Hughes
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by Talisman
All I Hear
by: TrainHow many lives must I live
How many lies must I hear
How many times must I, feel so blue
How many times must I, lose you
All I hear now
Is the sound of my heart breakin' down
Or losing ground
How many bridges must I burn
How many lessons must I learn
How many times must I ask you to stay
How many times will you push me out of your way
All I hear now
Is the sound of my heart breaking down - losing ground
All I hear now
Is the sound of my heart losing ground - slowing down
Maybe somebody will show me - a better way
Maybe somebody will know me - someday
How many times must I, hear your voice
Inside my dreams, your answering machine
You're always there and everywhere in between
All I hear now
Is the sound of my heart slowing down
Can ya hear the sound
All I hear now
Is the sound of my heart leaving town, breakin' down
Slowin' down, losin' ground, breakin' down and stopping here
All I hear now