IFT80

Intraflagellar transport protein 80 homolog (IFT80), also known as WD repeat-containing protein 56, is a protein that in humans is encoded by the IFT80 gene.

Function

IFT80 is part of the intraflagellar transport complex B and is necessary for the function of motile and sensory cilia.

Clinical significance

Mutations in the IFT80 gene are associated with asphyxiating thoracic dysplasia.

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.