Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3α) is an enzyme that in humans is encoded by the IDH3A gene.
Isocitrate dehydrogenases (IDHs) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]
For a long time he's been lucky man
No difference if it's good or bad
The trigger's his - the orders others
No way to stop the final blow
The message: here ya go
The countdown's on a roll
War against the world
All systems deadly armed
Machine, man, all in one
They're all oblivious to the crime
Braindead hero
Braindead hero - out of the sun he comes
Braindead hero
Braindead hero - feel the blazing guns
Now we got to blow his circuitry
Drain the poison from his veins
Degenerate - corrupt his memories
Fire at will - just do or die
The message: here ya go
The countdown's on a roll
War against the world
All systems deadly armed
Machine, man, all in one
They're all oblivious to the crime
Braindead hero
Braindead hero -like a hammer from the sky
Braindead hero
Braindead hero - supersonic cry
You better stay just where you are
Consequences in the fire
Braindead hero
Braindead hero - out of the sun he comes
Braindead hero