ID3 (gene)

DNA-binding protein inhibitor ID-3 is a protein that in humans is encoded by the ID3 gene.

Function

Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM]

Interactions

ID3 (gene) has been shown to interact with TCF3.

Repressors of ID3

BTG2 binds to the promoter of Id3 and represses its activity. By this mechanism, the upregulation of Id3 in the hippocampus caused by BTG2 ablation prevents terminal differentiation of hippocampal neurons.

See also

References

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Gene

A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.

Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term "having a gene" (e.g., "good genes," "hair colour gene") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.

Eugene (given name)

Eugene is a common (masculine) first name that comes from the Greek εὐγενής (eugenēs), "noble", literally "well-born", from εὖ (eu), "well" and γένος (genos), "race, stock, kin".Gene is a common shortened form. The feminine variant is Eugenia or Eugénie.

Male foreign-language variants include:

Notable people

Christianity

Military

Gene (novel)

Gene is a thriller novel by Stel Pavlou (born 1970), published in 2005 in England by Simon & Schuster. It is published in several languages with some title changes. The Italian edition has the title La Conspirazione del Minotauro (The Minotaur Conspiracy). The novel is about a fictional New York detective, James North, who in the process of hunting down a criminal, uncovers a genetics experiment to unlock past lives through genetic memory, therefore achieving a kind of immortality. In so doing North discovers his own origins, that of a soldier from the Trojan War who is reincarnated seven times through history, forced to confront his nemesis each time, all for the loss of his one true love.

Characters

Cyclades (born circa 1300 BC)

Incarnations of Cyclades

Athanatos (born circa 1500 BC)

Incarnations of Athanatos

ID3

ID3 is a metadata container most often used in conjunction with the MP3 audio file format. It allows information such as the title, artist, album, track number, and other information about the file to be stored in the file itself.

ID3 is also specified by Apple as a timed metadata in HTTP Live Streaming, carried as a PID in the main transport stream or in separate audio TS.

There are two unrelated versions of ID3: ID3v1 and ID3v2. ID3v1 takes the form of a 128-byte segment at the end of an MP3 file containing a fixed set of data fields. ID3v1.1 is a slight modification which adds a "track number" field at the expense of a slight shortening of the "comment" field. ID3v2 is structurally very different from ID3v1, consisting of an extensible set of "frames" located at the start of the file, each with a frame identifier (a three- or four-byte string) and one piece of data. 83 types of frames are declared in the ID3v2.4 specification, and applications can also define their own types. There are standard frames for containing cover art, BPM, copyright and license, lyrics, and arbitrary text and URL data, as well as other things. Three versions of ID3v2 have been documented, each of which has extended the frame definitions.

ID3 (disambiguation)

ID3 or ID-3 may refer to: