DNA-binding protein inhibitor ID-1 is a protein that in humans is encoded by the ID1 gene.
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
ID1 has been shown to interact weakly with MyoD but very tightly with ubiquitously expressed E proteins. E proteins heterodimerize with tissue restricted bHLH proteins such as Myod, NeuroD, etc. to form active transcription complexes so by sequestering E proteins, Id proteins can inhibit tissue restricted gene expression in multiple cell lineages using the same biochemical mechanism. Other interacting partners include CASK.
ID-1 or ID1 may refer to:
It's a temple for the worshipers of human decay
she'll be known to all their offspring as the queen of flies
in a mud infested ravel of a fallen house
lie the body of the woman who was never found
and the maggots eat away all sign of recognize
she'll be known to all their offspring as the queen of flies
her flesh will their shelter and her hair will be their hide
she'll be the home of pestulance, a vengance genocide
and her bones will be chalk that cleans the tidal wave
of anything organic, that's not worth to save
chorus
death is so unfasionable
flesh that falls of bones
the end comes creepin round the bend
death is so unfasionable
makes your colors gray
what makes me say such things
it makes you hate me
so this whore will be the mother of a million things
that longer down the line will complete a ring
when her bodyfat is turned into a stinking pond
its forgotten that she died with her makeup on
and the hamridge that she has upon her naked skull
was once a place for wirship for the white and dull
and the dress she wore that day that she was swept away