Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein-molecule that receives chemical-signals from outside a cell. When such chemical-signals bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, a receptor is a protein-molecule that recognises and responds to endogenous-chemical signals, e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Receptor-proteins are embedded in all cells' plasmatic-membranes; facing extracellular-(cell surface receptors), cytoplasmic (cytoplasmic-receptors), or in the nucleus (nuclear receptors). A molecule that binds to a receptor is called a ligand, and can be a peptide (short-protein) or another small molecule such as a neurotransmitter, hormone, pharmaceutical-drug, toxin, or parts of the outside of a virus or microbe. The endogenously designated-molecule for a particular receptor is referred to as its endogenous-ligand. E.g. the endogenous-ligand for the nicotinic-acetylcholine receptor is acetylcholine but the receptor can also be activated by nicotine and blocked by curare.

Loading... please wait...

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Receptor_(biochemistry)

Immune receptor

An immune receptor (or immunologic receptor) is a receptor, usually on a cell membrane, which binds to a substance (for example, a cytokine) and causes a response in the immune system.

Types

The main receptors in the immune system are pattern recognition receptors (PRRs), Toll-like receptors (TLRs), killer activated and killer inhibitor receptors (KARs and KIRs), complement receptors, Fc receptors, B cell receptors and T cell receptors.

References

1 2 3 Lippincott's Illustrated Reviews: Immunology. Paperback: 384 pages. Publisher: Lippincott Williams & Wilkins; (July 1, 2007). Language: English. ISBN 0-7817-9543-5. ISBN 978-0-7817-9543-2. Page 20

External links

immunologic receptor at the US National Library of Medicine Medical Subject Headings (MeSH)

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Immune_receptor

Beta-1 adrenergic receptor

The beta-1 adrenergic receptor (β₁ adrenoreceptor), also known as ADRB1, is a beta-adrenergic receptor, and also denotes the human gene encoding it. It is a G-protein coupled receptor associated with the Gs heterotrimeric G-protein and is expressed predominantly in cardiac tissue.

Receptor

Actions

Actions of the β₁ receptor include:

stimulate viscous, amylase-filled secretions from salivary glands

Increase cardiac output

Increase heart rate in sinoatrial node (SA node) (chronotropic effect)
Increase atrial cardiac muscle contractility. (inotropic effect)
Increases contractility and automaticity of ventricular cardiac muscle.
Increases conduction and automaticity of atrioventricular node (AV node)

Increase heart rate in sinoatrial node (SA node) (chronotropic effect)

Increase atrial cardiac muscle contractility. (inotropic effect)

Increases contractility and automaticity of ventricular cardiac muscle.

Increases conduction and automaticity of atrioventricular node (AV node)

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Beta-1_adrenergic_receptor

Hypnotized (1910 film)

Hypnotized, released in Britain as A Quack Hypnotist, is a 1910 American silent short drama produced by the Thanhouser Company. The film focuses on May Smalley and Jack, who loves her, who attend a traveling show that comes to their little town. The show consists of a hypnotist and a Hindu magician and proves to be a popular show, but the hypnotist who is becomes interest in May. The hypnotist lures May away by telling her that he has a message from the spirit world and later gets her to leave town with him. Jack knocks the magician down and takes his costume and follows the hypnotist and May back to their hotel, where he rescues her. Aside from William Russell's role in the film, the production and cast credits are unknown. The film was released on December 30, 1910, it was met with positive reviews. The film is presumed lost.

Plot

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Hypnotized_(1910_film)

Hypnotized (Plies song)

"Hypnotized" is the second single from Plies' debut album, The Real Testament. The track is produced by Akon, as well as featured. The video for the single was released. The single made the top twenty of the Billboard Hot 100, at #14. The song is featured on the soundtrack of the film Step Up 2 the Streets. A remix version was released featuring Rick Ross, Flo Rida and Webbie with a mixed beat.

Music Video

Directed by Gil Green, the video features Plies and Akon at a party in which Plies is attracted by women shaking their bodies that it makes him feel like he's going into a trance when seeing them.