SYVN1

E3 ubiquitin-protein ligase synoviolin is an enzyme that in humans is encoded by the SYVN1 gene.

This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.

References

Further reading

HRD

HRD may refer to:

  • Croatian dinar, a former currency of Croatia
  • Handel Reference Database
  • Harling Road railway station, in England
  • Hertzsprung-Russell diagram, in astronomy
  • Home Run Derby (Major League Baseball)
  • Hood River Distillers
  • Houston Roller Derby
  • HRD Motorcycles, a British motorcycle manufacturer
  • Human resource development
  • Human Resource Development Network, an Asian professional network
  • Human Rights Defence
  • Humboldt Roller Derby
  • Hurdles
  • Hurricane Research Division of the United States National Oceanic and Atmospheric Administration
  • HRD Motorcycles

    HRD Motors Ltd was a British motorcycle manufacturer in the 1920s. It was founded by Howard Raymond Davies. He had worked in motorcycling, and had raced with some success in the mid-twenties, but often not finishing due to unreliability. This inspired him to build a reliable performance motorcycle, using the advertising slogan "Built by a rider". Others also aimed at a similar market, like George Brough of Brough Superior motorcycles.

    After the First World War many motorcycle makers assembled their machines from engines and other major components sourced from different manufacturers. Davies' goal was to build a superior motorcycle from the best components available.

    Motorcycles were produced from 1924 to 1928, but the undercapitalised company, although having a reputation for performance, struggled to survive, and was ultimately sold to OK-Supreme, who then sold the name and goodwill to Phil Vincent, a motorcycle designer. The name was then incorporated into a new company, The Vincent HRD Company Ltd

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    Latest News for: hrd

    HRD Minister Lokesh pats Inter exam toppers for ‘upholding dignity of public education’

    The Hindu 16 Apr 2025
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    Andhra Pradesh HRD Minister Lokesh lays stone for 100-bed government hospital in Mangalagiri

    The Hindu 13 Apr 2025
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    Union HRD Minister’s intervention sought in Kancha Gachibowli land auction; Laxman raises issue in RS

    The Hindu 01 Apr 2025
    BJP vows to go to any extent to prevent the land auction; Party MLAs demand all party fact finding committee ....
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