Addition

Addition (often signified by the plus symbol "+") is one of the four basic operations of arithmetic, with the others being subtraction, multiplication and division. The addition of two whole numbers is the total amount of those quantities combined. For example, in the picture on the right, there is a combination of three apples and two apples together; making a total of 5 apples. This observation is equivalent to the mathematical expression "3 + 2 = 5" i.e., "3 add 2 is equal to 5".

Besides counting fruits, addition can also represent combining other physical objects. Using systematic generalizations, addition can also be defined on more abstract quantities, such as integers, rational numbers, real numbers and complex numbers and other abstract objects such as vectors and matrices.

In arithmetic, rules for addition involving fractions and negative numbers have been devised amongst others. In algebra, addition is studied more abstractly.

Addition has several important properties. It is commutative, meaning that order does not matter, and it is associative, meaning that when one adds more than two numbers, the order in which addition is performed does not matter (see Summation). Repeated addition of 1 is the same as counting; addition of 0 does not change a number. Addition also obeys predictable rules concerning related operations such as subtraction and multiplication.

ADD1

Alpha-adducin is a protein that in humans is encoded by the ADD1 gene.

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. Polymorphism in ADD1 is associated with hypertension.

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Further reading

ADD3

Gamma-adducin is a protein that in humans is encoded by the ADD3 gene.

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is composed of two distinct domains. The amino-terminal region is protease-resistant and globular in shape, while the carboxy-terminal region is protease-sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known.

Hotel (board game)

Hotel (known as Hotels in North America) is a dimensional real estate game created by Milton Bradley in 1986. It is similar to Square Mile and Prize Property. In Hotel the players are building resort hotels and attempting to drive their competitors into bankruptcy.

Gameplay

Players take turns moving around the board. Each square on the board is adjacent to one or two hotel properties. Most of the squares are either purchase squares or building squares.

Whenever a player lands on a purchase square which is adjacent to an unowned property they may buy that property by paying the purchase price. Once they own a property they may attempt to build on it whenever they land on a building square. A special dice is rolled to determine if permission to build is granted or denied. If it is denied the player must wait for a later turn.

When permission is granted to build the player may add new buildings or facilities to their property. Each hotel has from one to five buildings and a set of recreational facilities. The main building must be built first, followed by the other buildings then the facilities. The cost of each addition is listed on the deed card for the property.

City Sleeps

City Sleeps was an American rock band, formed in 2005. Originally called Smugface and playing an aggressive, somewhat progressive style of alternative rock in line with the nu metal of the late 1990s and early 2000s, it wasn't until around 2004 that this Atlanta-bred quintet changed its sound and image, and subsequently its name to City Sleeps.

Smugface consisted of core members Adriel Garcia (guitar), John Whitney (drums), and Elliott Sharp (vocals); early demos—produced by Rick Beato from Universal recording act Billionaire—got the band considerable attention in underground rock circles, as well as on the popular music site MP3.com. Members of alternative metal outfit Cold got wind of the group and were impressed, eventually bringing them to the attention of Limp Bizkit's Fred Durst, who almost signed Smugface to his Interscope imprint, Flawless Records.

Things were slowly changing internally, however, and by 2003, Smugface were noticeably transitioning into a much more melodic rock band, complete with big guitars and near-pop choruses. This new sound led to the band being noticed by producer John Feldmann (of the ska-punk band Goldfinger), who had previously worked successfully with similar groups like the Used and Story of the Year. He contacted the group in 2004 and the guys flew out to Los Angeles to record with him. City Sleeps—as they were then going by—were soon signed to Maverick/Warner Bros. Records, and by the following year, they had completed their debut, entitled Walker's Ridge, which was scheduled to be released in early 2006.

Hotel (Kid Ink song)

"Hotel" is a song by American hip hop recording artist Kid Ink. The song was released on January 9, 2015 by Tha Alumni Music Group, 88 Classic and RCA Records, as the second single from his third studio album Full Speed (2015). It was sent to US urban adult contemporary radio on January 27, 2015.

Background

After the commercial success of his previous single Show Me, Kid Ink linked up with recording artist Chris Brown to work on a song with songwriting and production team The Featherstones. At first the song was displayed as "track 5" on the iTunes Store album pre-order before it was released commercially as a single.

Music video

An animated music video was uploaded to Vevo June 9, 2015.

Charts

References