HLA-A11

HLA-A11 (A11) is a human leukocyte antigen serotype within HLA-A "A" serotype group. The serotype is determined by the antibody recognition of α¹¹ subset of HLA-A α-chains. For A11, the alpha "A" chain are encoded by the HLA-A*11 allele group and the β-chain are encoded by B2M locus. This group currently is dominated by A*1101. A11 and A*11 are almost synonymous in meaning.

A11 is more common in East Asia than elsewhere, it is part of a several long haplotypes that appear to have been frequent in the ancient peoples of Asia.

Serotype

Serotyping of A11 demonstrates better recognition of the *1101 gene products and poorer recognition of other A*11 gene products. There are ~40 recognized alleles of A*11. There is only one null classified as A11.

In infectious disease

Associations have been observed between A11 and familial otosclerosis, pulmonary tuberculosis,leprosy, and cytomegalovirus infection with epilepsy. These and other studies suggest an involvement between A11 and secondary effects of certain herpes virus infections. A11 was also found increase in supraglottic cancer with poor 3 year survival. In osteosarcoma A11 was found elevated.

A11

A11, A 11 or A-11 may refer to:

Military

Roads

Other

A11 motorway (Portugal)

A11 is a motorway (freeway) in Portugal. It connects Apúlia to Amarante via Guimarães. A11 is operated by Aenor - Auto-Estradas do Norte, S.A.

English Opening

The English Opening is a chess opening that begins with the move:

A flank opening, it is the fourth most popular and, according to various databases, anywhere from one of the two most successful to the fourth most successful of White's twenty possible first moves. White begins the fight for the centre by staking a claim to the d5 square from the wing, in hypermodern style. Although many lines of the English have a distinct character, the opening is often used as a transpositional device in much the same way as 1.Nf3 – to avoid such highly regarded responses to 1.d4 as the Nimzo–Indian and Grünfeld defences, and is considered reliable and flexible.

The English derives its name from the English (unofficial) world champion, Howard Staunton, who played it during his 1843 match with Saint-Amant and at London 1851, the first international tournament. It did not inspire Staunton's contemporaries, and only caught on in the twentieth century. It is now recognised as a solid opening that may be used to reach both classical and hypermodern positions. Mikhail Botvinnik, Tigran Petrosian, Anatoly Karpov, Garry Kasparov and Magnus Carlsen employed it during their world championship matches. Bobby Fischer created a stir when he switched to it from his customary 1.e4 late in his career, employing it against Lev Polugaevsky and Oscar Panno at the Palma de Mallorca Interzonal in 1970 and in his 1972 world championship match against Boris Spassky.

HLA

HLA may refer to:

Biochemistry

Computing

Engineering

People

Politics

HLA (radio station)

Coordinates: 36°23′15″N 127°21′59″E / 36.38753°N 127.36650°E / 36.38753; 127.36650 (HLA time signal antenna) HLA is a time signal radio station in Daejeon, South Korea, operated by the Korea Research Institute of Standards and Science. Established on November 24, 1984, it transmits a 2 kW signal on 5 MHz (±0.01 Hz). Originally only transmitted for 7 hours per day (01:00–08:00), 5 days per week (M–F), it is continuous as of 2011, There are over 100 users of the signal in Korea.

It broadcasts a time signal similar to that of the WWV and WWVH stations with which it shares a frequency:

References

External links