Hit!
Hit! is a 1973 action film directed by Sidney J. Furie and starring Billy Dee Williams and Richard Pryor. It is about a federal agent trying to destroy a drug zone after his daughter dies from a heroin overdose.
An alternate title for the film was Goodbye Marseilles.
Note
Many of the people, both cast and crew, involved in this film had previously worked on Lady Sings the Blues (1972).
The role of Nick Allen was originally written for Steve McQueen.
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Den (newspaper)
Den (Ukrainian: День, The Day) is a Kiev-based, centrist daily broadsheet newspaper.
History and profile
Den was founded in 1996. The paper is linked to former prime minister Yevhen Marchuk, his wife Larysa Ivshyna is the paper's editor-in-chief. Den has been supporting NATO and ties with the West.
The paper is also notable by its annual photography contest, being the main photo event in Ukraine.
Den is a member of UAPP.
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Den (room)
A den is a small room in a house where people can pursue activities in private.
In the United States, the type of rooms described by the term den varies considerably by region. It is used to describe many different kinds of bonus rooms, including studies, family rooms, home offices, libraries, home cinemas, or even spare bedrooms. In some places, particularly in parts of the British Isles, a small den may be known as a snug.
While living rooms tend to be used for entertaining company on formal occasions, dens, like other family rooms, tend toward the more informal. In houses that do not have dedicated family rooms or recreation rooms, a den may fill that niche. Dens can also be private areas primarily used by adult members of the household, possibly restricting access to the room by their children. Dens with home theater systems and large screen televisions may be referred to as media rooms instead. Most den floors are made out of wood, carpet, or floor tiling.
Dens can serve the same purpose as cabinets in the past, becoming a modern man cave—a place for men to gather and entertain. In such cases, the design and decor may be distinctively masculine.
DEN 1048-3956
DEN 1048-3956 is a brown dwarf about 13 light years from Earth in the southern constellation of Antlia, among the closest interstellar objects to Earth. This substellar object is very dim with an apparent magnitude of about 17, and will require a telescope with a camera to be seen. It was discovered in 2000 by Xavier Delfosse (Institute of Astrophysics of the Canary Islands, now Observatoire de Grenoble) and Thierry Forveille (Canada–France–Hawaii Telescope Corporation), with the assistance of nine other astronomers.
In 2005 a powerful flare from this object was detected by radio astronomy.
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Proposed top-level domain
The Domain Name System of the Internet consists of a set of top-level domains which constitute the root domain of the hierarchical name space and database. In the growth of the Internet, it became desirable to expand the set of initially six generic top-level domains in 1984. As a result new top-level domain names have been proposed for implementation by ICANN. Such proposals included a variety of models ranging from adoption of policies for unrestricted gTLDs that could be registered by anyone for any purpose, to chartered gTLDs for specialized uses by specialized organizations. In October 2000, ICANN published a list of proposals for top-level domain strings it had received.
Geographic proposals
MED28
Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. It forms part of the Mediator complex.
Function
Subunit Med28 of the Mediator may function as a scaffolding protein within Mediator by maintaining the stability of a submodule within the head module, and components of this submodule act together in a gene-regulatory programme to suppress smooth muscle cell differentiation. Thus, mammalian Mediator subunit Med28 functions as a repressor of smooth muscle-cell differentiation, which could have implications for disorders associated with abnormalities in smooth muscle cell growth and differentiation, including atherosclerosis, asthma, hypertension, and smooth muscle tumours.
Interactions
MED28 has been shown to interact with Merlin,Grb2 and MED26.
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This article incorporates text from the public domain Pfam and InterPro IPR021640
Further reading
MED6
Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the MED6 gene.
Protein family
This family of proteins represent the transcriptional mediator protein subunit 6 that is required for activation of many RNA polymerase II promoters and which are conserved from yeast to humans.
Interactions
MED6 has been shown to interact with:
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Further reading
External links
This article incorporates text from the public domain Pfam and InterPro IPR007018
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