Hib vaccine

Haemophilus influenzae type B vaccine is a vaccine used to prevent Haemophilus influenzae type b (Hib) infection. In countries that include it as a routine vaccine, rates of severe Hib infections have decreased more than 90%. It has therefore resulted in a decrease in the rate of meningitis, pneumonia, and epiglottitis.

It is recommended by both the World Health Organization and Centers for Disease Control and Prevention. Two or three doses should be given before six months of age. The first dose is recommended around six weeks of age with four weeks between doses. If only two doses are used, another dose later in life is recommended. It is given by injection into a muscle.

Severe side effects are uncommon. About 20 to 25% of people develop pain at the site of injection while about 2% develop a fever. There is no clear association with severe allergic reactions. The Hib vaccine is available by itself, in combination with the diptheria/tetanus/pertussis vaccine, and in combination with the hepatitis B vaccine, among others. All Hib vaccines that are currently used are conjugate vaccine.