Hepatocyte

A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 70-85% of the liver's mass. These cells are involved in:

  • Protein synthesis
  • Protein storage
  • Transformation of carbohydrates
  • Synthesis of cholesterol, bile salts and phospholipids
  • Detoxification, modification, and excretion of exogenous and endogenous substances
  • Initiation of formation and secretion of bile
  • Structure

    The typical hepatocyte is cubical with sides of 20-30 µm, (in comparison, a human hair has a diameter of 17 to 180 µm). The typical volume of a hepatocyte is 3.4 x 10−9 cm3.

    Smooth endoplasmic reticulum is abundant in hepatocytes, whereas most cells in the body have only small amounts.

    Histology

    Hepatocytes display an eosinophilic cytoplasm, reflecting numerous mitochondria, and basophilic stippling due to large amounts of rough endoplasmic reticulum and free ribosomes. Brown lipofuscin granules are also observed (with increasing age) together with irregular unstained areas of cytoplasm; these correspond to cytoplasmic glycogen and lipid stores removed during histological preparation. The average life span of the hepatocyte is 5 months; they are able to regenerate.

    Podcasts:

    PLAYLIST TIME:

    Hope

    by: Twista

    Artist: Twista f/ Cee-Lo
    Album: Kamikaze
    Song: Hope
    Typed by: AArsdam@aol.com
    Man I know we had a lot of tragedies lately
    I just wanna say rest in peace to Aaliyah
    Rest in peace to Left-Eye, rest in peace to Jam Master Jay
    And everybody lost in the Twin Towers, and everybody lost period
    All we got is hope..
    [Verse 1: Twista]
    I wish the way I was livin' could stop
    Servin' rocks, knowin' the cops is hot when I'm on the block
    And I - wish my brother would've made bail
    So I won't have to travel six hours to see him in jail
    And I - wish that my grandmother wasn't sick
    Or that we would just come up on some stacks and hit a lick (I wish)
    And I - wish my homies wouldn't have to suffer
    When the streets get the upper hand understand we lose a brother
    And I - wish I could go deep in the zone
    And lift the spirits of the world with words within this song (I wish)
    And I - wish I could teach us all to fly
    Take away the pain out your hands and help you hold 'em high
    And I - wish God had never gave the men power
    To be able to hurt the people inside the Twin Towers (I wish)
    And I - wish God would've turned they hearts righteous
    When they started to take innocent lives and become snipers
    But uh - we will never break though they devastate
    We shall motivate, and we gotta pray, all we got is faith
    Instead of thinkin' about who gon' die today
    The Lord is gon' help you feel better so you ain't gotta cry today
    Sit at the light so long
    And then we gotta move straight forward cause we bite so strong
    So when right go wrong
    Just say a lil' prayer, get your money man, life goes on... (Let's go)
    [Chorus: Cee-Lo]
    Cause I'm hopeful, yes I am, hopeful for today
    Take this music and use it, let it take you away
    And be hopeful, hopeful, and He'll make a way
    I know it ain't easy but - that's okay
    Just be hopeful
    [Verse 2: Twista]
    I wish that you would show some love
    Instead of hatin' so much when you see some other people comin' up (I wish)
    I wish I could teach the world to sing
    Write some music and have them trippin' off the joy I bring
    Shit - I wish that we can hold hands
    Listenin' instead of dissin', lessons from a grown man (I wish)
    And I - wish the families that lack but got love
    Get some stacks, brand new shack, and a 'Llac that's on dubs
    And I - wish we could keep achieving wonders
    See the vision of the world through the eyes of Stevie Wonder (I wish)
    You feel me - and I hope all the kids eat
    And don't nobody in my family see six feet - ya dig?
    I hope the mothers stand strong
    You can make it whether you with him or your man's gone (I wish)
    And I - wish I could give every celly some commissary
    And no popo bring the heat on our peace like they did R. Kelly
    And I - wish that D.O.C. could scream again
    And bullets could reverse and Pac and Biggie breathe again
    Shit - and one day they can speak again
    I wish that we only saw good news every time we look at CNN
    I wish that enemies could talk
    And that Super-homie Christopher Reeve could still walk (I wish)
    I wish that we could walk the path stay doin' the right thing
    Hustle hard so them kids maintain up in the game (Let's go)
    [Chorus: Cee-Lo]
    Cause I'm hopeful, yes I am, hopeful for today
    Take this music and use it, let it take you away
    And be hopeful, hopeful, and He'll make a way
    I know it ain't easy but - that's okay
    Just be hopeful
    [Verse 3: Twista]
    Wish the earth wasn't so apocaliptic
    I try to spread my message to the world the best way that I can give it
    We can make it, always so optimistic
    If you don't listen, gotta live my life the best way that I can live it
    I pray for justice when we go to court
    Wish it was all good so the country wouldn't have to go to war
    Why can't we kick it and just 'em on
    And in the famous words of Mister King, 'why can't we all just get along?'
    Hope we can find a better way to shop in peace
    And I - hope we find a better way to cop for keys
    And I - wish everybody would just stop and freeze
    And ask - why are fulfilling these downfalls and these prophecies
    You can be wrong if it's you doubtin'
    With the faith of a mustard seed, you can move mountains
    And only the heavenly father can ease the hurt
    Just let it go and keep prayin' on your knees in church (Let's go)
    [Chorus: Cee-Lo]
    Cause I'm hopeful, yes I am, hopeful for today
    Take this music and use it, let it take you away
    And be hopeful, hopeful, and He'll make a way
    I know it ain't easy but - that's okay
    Just be hopeful
    (Repeat)
    Na na na na na na na na na
    Just be hopeful
    (Repeat)
    Na na na na na na na na na
    Na na na na na na na




    ×