Calciphylaxis

Calciphylaxis, or calcific uremic arteriolopathy (CUA), is a syndrome of vascular calcification, thrombosis and skin necrosis. It is seen mostly in patients with Stage 5 chronic kidney disease, but can occur in the absence of renal failure. It results in chronic non-healing wounds and is usually fatal. Calciphylaxis is a rare but serious disease, believed to affect 1-4% of all dialysis patients.

Calciphylaxis is one type of extraskeletal calcification. Similar extraskeletal calcifications are observed in some patients with hypercalcemic states, including patients with milk-alkali syndrome, sarcoidosis, primary hyperparathyroidism, and hypervitaminosis D.

Signs and symptoms

The first skin change in calciphylaxis lesions are mottling of the skin and induration in a livedo reticularis pattern. As tissue thrombosis and infarction occurs, a black, leathery eschar in an ulcer with adherent black slough are found. Surrounding the ulcers is usually a plate-like area of indurated skin. These lesions are always extremely painful and most often occur on the lower extremities, abdomen, buttocks, and penis. Because the tissue has infarcted, wound healing seldom occurs, and ulcers are more likely to become secondarily infected. Many cases of calciphylaxis end with systemic bacterial infection and death.

Heart of Stone (Star Trek: Deep Space Nine)

"Heart of Stone" is the fourteenth episode of the third season of the American science fiction television series Star Trek: Deep Space Nine, and originally aired on February 6, 1995 in broadcast syndication. The story was written by Ira Steven Behr and Robert Hewitt Wolfe, while the episode was directed by Alexander Singer and the score was created by David Bell.

Set in the 24th century, the series follows the adventures on Deep Space Nine, a space station located near a stable wormhole between the Alpha and Gamma quadrants of the Milky Way Galaxy. In this episode, Odo (René Auberjonois) and Major Kira Nerys (Nana Visitor) are trapped on a small moon near the Badlands, while on the station Nog (Aron Eisenberg) tries to get Commander Benjamin Sisko's (Avery Brooks) support for his application to Starfleet Academy.

The idea behind the main plot was inspired by a scene from the novel Sometimes a Great Notion. However, the rock prop used was unpopular with the cast and crew, and post-production effects were required. The episode was the first of an ongoing plot thread with Nog entering Starfleet, which initially concerned Eisenberg as he thought he was being written out of the show. The episode was the fourth most watched episode of the third series, with 8.3 million viewers. Critical response was mixed, with negative comments directed at the idea that the situation was created by the female Founder (Salome Jens).

Heart of Stone (1950 film)

Heart of Stone (German: Das kalte Herz) is an East German fantasy film directed by Paul Verhoeven. The first East German film made in Agfacolor, it was released in 1950.

Plot

Peter, a woodsman and his mother live in the Black Forest where he exists by selling charcoal. Stung by the ridicule of the wealthier inhabitants of the village and desiring to marry the beautiful Lisbeth, he sees his only chance for prosperity by locating a good forest spirit, the small Glasmännlein who grants him two wishes at first, then a third wish later. Peter wishes for wealth that he purchases a glassworks but due to his inexperience the glassworks fails and he gambles his money away.

Unable to marry Lisbeth due to his being pursued by creditors, Peter locates a dark forest spirit, Holländer-Michel, to make more wishes for wealth. Holländer-Michel agrees to grant him wealth, but only in exchange for his heart that Holländer-Michel replaces with one made of stone. Holländer-Michel shows that the wealtheir inhabitants of the village already have done so and shows Peter their hearts that he displays on the wall. Peter agrees and becomes a ruthlessly successful businessman but at the cost of Lisbeth and his happiness.

Cher (TV series)

Cher was an American variety show that premiered on CBS in 1975. It was hosted by singer-actress, Cher. The show had many famous musical guests. It followed a TV special featuring Elton John, Bette Midler, and Flip Wilson as guests. Cher premiered at 7.30pm on Sunday, February 16, 1975 and finished the season ranked 1st among variety shows and 22nd among all programs, with a 21.3 average household share.

Overview

The show featured Cher interviewing various celebrity guests ranging from musicians, actors, and pop culture figures. In addition to interviews, the series also featured comedy skits, and comedic field reports. Cher would also perform her songs along with a live band.

References

External links

  • Cher at the Internet Movie Database
  • Cher at TV.com
  • Clueless (film)

    Clueless is a 1995 American coming-of-age comedy film. It is loosely based on Jane Austen's 1815 novel Emma. It stars Alicia Silverstone (in the lead role), Stacey Dash, Paul Rudd, and Brittany Murphy. The film is set in Beverly Hills and was written and directed by Amy Heckerling and produced by Scott Rudin. It was released in the United States on July 21, 1995.

    The film grossed $56 million in the United States and has developed a cult following.

    The film spun off a television sitcom and a series of books.

    Plot

    Cherilyn "Cher" Horowitz is a good-natured but superficial girl who is attractive, popular, and extremely wealthy. A few months shy of her sixteenth birthday, she has risen to the top of the high school social scene. She lives in a Beverly Hills mansion with her father Mel, a ferocious $500-an-hour litigator; her mother died from a freak accident during a routine liposuction procedure when Cher was a baby. Cher's best friend is Dionne Davenport, who is also rich, pretty, and hip, and understands what it's like to be envied. Though Dionne has a long-term relationship with popular student Murray, Cher claims that it is a pointless endeavor.

    Cher (2008–2011 residency show)

    Cher was a residency show by American entertainer Cher at Caesars Palace in Las Vegas, Nevada. For the three-year engagement, Cher received $60 million. Performing at The Colosseum at Caesars Palace, the first show occurred on May 6, 2008 and the last show was on February 5, 2011. Cher planned to perform 200 dates over a three-year period but due to eight cancellations only 192 shows were done. The show included 14 dancers and four aerialists, with a total of 17 costumes designed by Bob Mackie.

    Set list

    This setlist is representative for the opening concert on May 6, 2008. It doesn't represent all shows.

  • "Opening"
  • "I Still Haven't Found What I'm Looking For"
  • "Song for the Lonely"
  • "I've Gotta Be Me" (Interlude)
  • "All or Nothing"
  • "I Found Someone"
  • "Love Is a Battlefield"
  • "It's the Little Things" (Interlude)
  • "The Beat Goes On"
  • "All I Really Want to Do"
  • "Gypsys, Tramps & Thieves" (Medley part 1)
  • "Dark Lady" (Medley part 2)
  • "Half-Breed"
  • "Disco Inferno" (Medley part 1)
  • "YMCA" (Medley part 2)
  • Podcasts:

    Cher

    ALBUMS

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    PLAYLIST TIME:

    Heart Of Stone

    by: Erasure

    I cry for your heart of stone
    I'm gonna wait until you come home
    Oh why I am I alone?
    I'm as good as dead yeah
    Ooh I lost my sense of passion and direction
    To protect myself from hurting and despair
    Listen to my heart my soul is aching
    Fool or saint?
    Cause you went and left me
    And you so upset me
    I can't believe that you would ever find it easy
    To walk away as if you'd never really cared
    Did you expect that I'd give in and beg for mercy
    Out in the gutter
    Out in the gutter
    I cry for your heart of stone
    I'm gonna wait until you come home
    Oh why I am I alone?
    I'm as good as dead yeah
    Ooh I look back on the first night with affection
    And if you had a heart you'd remember too
    The way we used to run around like little children
    Fool or saint?
    My mother told me
    You'd be no good for me
    I cry for your heart of stone
    I'm gonna wait until you come home
    Oh why I am I alone?
    I'm as good as dead yeah
    Out in the gutter
    I got to break that heart of stone
    I cry for your heart of stone
    (I been worried about you baby)
    Oh why I am I alone?
    (I been worried about you baby)
    I'm as good as dead yeah
    (I want you back)




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