A head transplant is a surgical operation which involves the grafting of one organism's head onto the body of another. It should not be confused with another, hypothetical, surgical operation, the brain transplant. Head transplantation involves decapitating the patient.
Charles Claude Guthrie succeeded in grafting one dog's head onto the side of another's neck on 21 May 1908.
Vladimir Demikhov experimented with dog head transplantation in the Soviet Union in the 1950s. His transplant subjects typically died due to immune reactions.
In 1959, China announced they had succeeded in transplanting the head of one dog to the body of another twice.
Dr. Vladimir Demikhov's work, among others, was deeply influential for the future science of organ transplant, as he pioneered many different forms of transplant in the 1940s and 1950s, including the use of immuno-suppressants. His work was well known by other scientists and during the 1950s and 1960s, numerous heart transplants were performed on dogs in the United States by Dr. Norman Shumway of Stanford University and Dr. Richard Lower of the Medical College of Virginia. The first human heart transplant was performed by Christiaan Barnard in South Africa, in 1967, however, as they did not have the chemical agents to utilize immuno-suppressants, the patient receiving the transplant did not do very well.