HLA-DQ6
HLA-DQ6 (DQ6) is a human leukocyte antigen serotype within HLA-DQ (DQ) serotype group. The serotype is determined by the antibody recognition of β6 subset of DQ β-chains. The β-chain of DQ isoforms are encoded by HLA-DQB1 locus and DQ6 are encoded by the HLA-DQB1*06 allele group. This group currently contains many common alleles, DQB1*0602 is the most common. HLA-DQ6 and DQB1*06 are almost synonymous in meaning. DQ6 β-chains combine with α-chains, encoded by genetically linked HLA-DQA1 alleles, to form the cis-haplotype isoforms. For DQ6, however, cis-isoform pairing only occurs with DQ1 α-chains. There are many haplotypes of DQ6.
Serology
Alleles
DQB1*0601
DQB1*0601 is generally linked to DQA1*0103 as 6.1 haplotype. This haplotype is more common in Japan and other parts of East Asia.
DQB1*0602
DQB1*0602 is commonly linked to DQA1*0102 to form 6.2 haplotype. DQ6.2 and is common from Central Asia into Western Europe, *0602 is also linked to DQA1*0103 in parts of Asia.
DQB1*0603
DQB1*0603 is commonly linked to DQA1*0103 as 6.3 and is common from Central Asia into Western Europe, *0603 is also linked to DQA1*0102 in parts of Asia. In Europe it is most common in the Netherlands.
Podcasts:
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So Happy I Could Die
by: Lady GagaEh-eh, eh-eh, yeha, yeha
Eh-eh, eh-eh, aha, aha
Eh-eh, eh-eh, yeha, yeha
Eh-eh, eh-eh, aha, aha
I love that lavender blonde
The way she moves, the way she walks
I touch myself, can't get enough
And in the silence of the night
Through all the tears and all the lies
I touch myself, and it's alright
Just give in, don't give up, baby
Open up your heart and your mind to me
Just know when that glass is empty
That the world is gonna bend, yeah
Happy in the club with a bottle of red wine
Stars in our eyes 'cause we're having a good time
Eh-eh, eh-eh, so happy I could die
Be your best friend, yeah, I'll love you forever
Up in the clouds, we'll be higher than ever
Eh-eh, eh-eh, so happy I could die, and it's alright
Eh-eh, eh-eh, yeha, yeha
Eh-eh, eh-eh, aha, aha
Eh-eh, eh-eh, yeha, yeha
Eh-eh, eh-eh, aha, aha
I am as vain as I allow
I do my hair, I gloss my eyes
I touch myself all through the night
And when something falls out of place
I take my time, I put it back
I touch myself 'til I'm on track
Just give in, don't give up, baby
Open up your heart and your mind to me
Just know when that glass is empty
That the world is gonna bend, yeah
Happy in the club with a bottle of red wine
Stars in our eyes 'cause we're having a good time
Eh-eh, eh-eh, so happy I could die
Be your best friend, yeah, I'll love you forever
Up in the clouds, we'll be higher than ever
Eh-eh, eh-eh, so happy I could die and it's alright
So happy I could die, and it's alright
So happy I could die, and it's alright
Eh-eh, eh-eh, yeha, yeha
Eh-eh, eh-eh, aha, aha
Eh-eh, eh-eh, yeha, yeha
Eh-eh, eh-eh, aha, aha
Happy in the club with a bottle of red wine
Stars in our eyes 'cause we're having a good time
Eh-eh, eh-eh, so happy I could die
Be your best friend, yeah, I'll love you forever
Up in the clouds, we'll be higher than ever
Eh-eh, eh-eh, so happy I could die, and it's alright
Happy in the club with a bottle of red wine
Stars in our eyes 'cause we're having a good time
Eh-eh, eh-eh, so happy I could die
Be your best friend, yeah, I'll love you forever
Up in the clouds, we'll be higher than ever