HIV and pregnancy

Women diagnosed with HIV/AIDS may transmit the infection to their child during pregnancy. The infection may spread during pregnancy, childbirth, or breastfeeding. However, the risk of mother-to-child transmission of HIV may be reduced by the use of HIV medications known as antiretroviral therapy (ART). These medications may be used by women before, during, and after pregnancy. After delivery, children are also given the medication to reduce the risk of infection. Because HIV may be spread through breastmilk, mothers with the infection should avoid breastfeeding their children.

Infection with HIV/AIDS is not a contraindication to pregnancy. Women with the disease may choose to become pregnant if they desire, however, they are encouraged to talk with their doctors beforehand. Some women are unaware they have the disease until they become pregnant. In this case, they should begin antiretroviral therapy as soon as possible. With the appropriate treatment, the risk of mother-to-child infection can be reduced to below 1%. Without treatment, the risk of transmission is 15-45%.

.hiv

.hiv is a generic top-level domain (gTLD) proposed by the Berlin-based nonprofit dotHIV and owned by Uniregistry as of September 2014. It is the first open charitable gTLD and its ICANN designation states that the domain's operator is precluded from making a profit. Funds raised from .hiv domain sales will initially benefit projects to increase access to HIV/AIDS treatment in Rwanda, South Africa, Turkey, and the United States.

History

The top-level domain (TLD) was inspired by the anti-HIV/AIDS campaign by thjnk, a German advertising agency. thjnk's co-owner Michael Trautmann established dotHIV gemeinnütziger e.V. as a nonprofit and applied for the .hiv TLD. Despite the global relevance of HIV/AIDS, dotHIV was the only applicant for the .hiv TLD. The company signed a registration contract with ICANN in March 2014. Domains were made available for select companies and individuals during the July "sunrise" period, becoming generally available in August 2014. hiv became the first open charitable TLD and, according to one press release, "opens up a dedicated namespace that brings website owners together behind one goal: The end of AIDS".

HIV

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.

HIV infects vital cells in the human immune system such as helper T cells (specifically CD4⁺ T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4⁺ T cells through a number of mechanisms, including pyroptosis of abortively infected T cells,apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4⁺ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4⁺ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.

Hiv, Iran

Hiv (Persian: هيو‎‎, also Romanized as Hīv) is a village in Hiv Rural District, in the Central District of Savojbolagh County, Alborz Province, Iran. At the 2006 census, its population was 8,061, in 2,247 families.

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