Metabotropic glutamate receptor 4
Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene.
Together with GRM6, GRM7 and GRM8 it belongs to group III of the metabotropic glutamate receptor family. Group III receptors are linked to the inhibition of the cyclic AMP cascade. Activation of GRM4 has potential therapeutic benefits in the treatment of parkinson's disease. Splice variant "taste-GRM4" is involved in the perception of umami taste.
Ligands
Orthosteric
Positive allosteric modulators (PAMs)
References
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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Time Traveler
by: Chromium"Welcome all tourists coming to board number 3-10-9er
I hope you have a pleasant journey back in time.
Thank You!"
Time, We travel through time
Ooh, What a delight
"Around the gate 7, is the attendants station,
where the passengers are boarding the planes.
Please stay there waiting with your luggage.
Thank You!"
Time, We travel through time
Ooh, What a delight
Time, We'll leave it behind
Ooh, What a delight
"This is your Captain speaking.
We are now moving back into the 20th Century
at approximately -2 Years per minute.
Please keep your seat belts fastened
as we will shortly be experiencing some time
turbulence"
"Let's follow from back to forward.
And passengers please make their way to Gate 51.
Thank You!"
Time,
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Time,
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Time,
We travel through time