Corythomantis greeningi (Greening's frog) is a venomousfrog species in the family Hylidae. Endemic to eastern Brazil, it lives in Caatinga savanna habitat. It is usually situated on vegetation, including in bromeliads, and on rock outcrops. Breeding occurs in temporary streams. Although suffering from habitat loss, it is not considered threatened by the IUCN.
Unlike most poison dart frogs which merely secrete venom from their skin, this species is equipped with skull spines capable of injecting venom into other animals or human hands via headbutting, a tactic it shares with Aparasphenodon brunoi.