Gone! (The Cure song)

"Gone!" is a single released by the British group The Cure in 1996, reaching number sixty on the UK Singles Chart. The song was released on the album Wild Mood Swings.

History

A video was recorded for the song at a live concert in Los Angeles in August 1996. The song did not achieve commercial success as it was played infrequently at concerts, although the band did perform it on Later with Jools Holland.

Track listing

UK CD1

UK CD2

Personnel

External links

Gone (Pearl Jam song)

"Gone" is a song by the American rock band Pearl Jam. Written by vocalist Eddie Vedder, "Gone" was released through digital music stores on October 7, 2006 as the third single from the band's eighth studio album, Pearl Jam (2006). The song reached number 40 on the Billboard Modern Rock Tracks chart.

Origin and recording

"Gone" was written by vocalist Eddie Vedder on September 30, 2005, in the Room 1152 (where the band stayed that night), of the Borgata Hotel, located in Atlantic City, New Jersey. It debuted the next night in a solo performance by Vedder at the band's October 1, 2005 concert in Atlantic City, New Jersey at the Borgata Events Center. The band recorded a demo version of the song that was released as a part of the 2005 Holiday single available to fan club members. Vedder on the song:

Lyrics

"Gone" is about leaving everything behind and moving along. The song brings into perspective perceptions that all is not lost if one chooses to incorporate change. When the song was performed on VH1 Storytellers in 2006, Vedder introduced it as "a car song." In an interview Vedder stated:

Mo Hayder

Mo Hayder (born 1962) is a British author of crime and thriller fiction.

She is the author of eight novels. Her debut, Birdman, was published in January 2000 and was an international bestseller. Her second novel, The Treatment, was a Sunday Times bestseller and won the 2002 WH Smith Thumping Good Read award. Her third novel, Tokyo, was published in May 2004 and was another Sunday Times bestseller. Tokyo was published as The Devil of Nanking in the United States in March 2005. Pig Island was her fourth best seller and was published in April 2006. Pig Island was nominated for both a Barry Award for Best British crime novel, and a CWA dagger. Her fifth book, Ritual was the first in The Walking Man series, and was nominated for CWA Ian Fleming Steel Dagger award. Skin is the second book in The Walking Man series, and was released in early 2009. Gone, the third book in The Walking Man series, was released in February 2011; it won the Edgar Award for Best Novel. Her latest novel is Hanging Hill, published 2011.

Ṛta

In the Vedic religion, Ṛta (Sanskrit ऋतं ṛtaṃ "that which is properly/excellently joined; order, rule; truth") is the principle of natural order which regulates and coordinates the operation of the universe and everything within it. In the hymns of the Vedas, Ṛta is described as that which is ultimately responsible for the proper functioning of the natural, moral and sacrificial orders. Conceptually, it is closely allied to the injunctions and ordinances thought to uphold it, collectively referred to as Dharma, and the action of the individual in relation to those ordinances, referred to as Karma – two terms which eventually eclipsed Ṛta in importance as signifying natural, religious and moral order in later Hinduism. Sanskrit scholar Maurice Bloomfield referred to Ṛta as "one of the most important religious conceptions of the Rig Veda", going on to note that, "from the point of view of the history of religious ideas we may, in fact we must, begin the history of Hindu religion at least with the history of this conception".

Royal Thai Army Radio and Television Channel 5

Royal Thai Army Radio and Television Channel 5 (สถานีวิทยุโทรทัศน์กองทัพบก) is a terrestrial television station of the Royal Thai Army (RTA). It was the second television station in Thailand. It began broadcasting on 25 January 1958 in very high frequency (VHF).

History

Broadcast signals go through a network of 31 transmitters dotted around the country. Daily transmission is 24 hours, but regular programs begins at 05:00, ending at 03:00 the next day. Between 03:00 and 05:00 TV5 broadcasts teleshopping.

Channel 5 broadcasts in VHF on Channel 5 for analogue broadcasting and ultra high frequency (UHF) channel 36 for digital broadcasting.

Channel 5 is also available over TrueVisions on Channel 2.

Criticism and controversy

Channel 5 has been criticized in the past for not taking certain programming seriously and even taking some programs off the air without letting it finish the season run.

References

See also

RTA 408

RTA 408 is a second generation member of the synthetic oleanane triterpenoid compounds and currently in clinical development by Reata Pharmaceuticals. Preclinical studies have demonstrated that RTA 408 possesses antioxidative and anti-inflammatory activities and the ability to improve mitochondrial bioenergetics. RTA 408 is currently under clinical investigation for a variety of indications, including Friedreich’s ataxia, mitochondrial myopathies, immunooncology, and prevention of corneal endothelial cell loss following cataract surgery.

Mechanism of action

The effects of RTA 408 and related synthetic triterpenoid compounds have been documented in over 200 peer-reviewed scientific manuscripts. The mechanism of action of RTA 408 and its related compounds has been demonstrated to be through a combination of activation of the antioxidative transcription factor Nrf2 and inhibition of the pro-inflammatory transcription factor NF-κB.

Nrf2 transcriptionally regulates multiple genes that play both direct and indirect roles in producing antioxidative potential and the production of cellular energy (i.e., adenosine triphosphate or ATP) within the mitochondria. Consequently, unlike exogenously administered antioxidants (e.g., vitamin E or Coenzyme Q10), which provide a specific and finite antioxidative potential, RTA 408, through Nrf2, broadly activates intracellular and mitochondrial antioxidative pathways, in addition to pathways that may directly increase mitochondrial biogenesis (such as PGC1α) and bioenergetics.