GMP
GMP may refer to:
Business and organisations
Science and technology
P-selectin
P-selectin is a protein that in humans is encoded by the SELP gene.
P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets P-selectin is stored in α-granules.
Other names for P-selectin include CD62P, Granule Membrane Protein 140 (GMP-140), and Platelet Activation-Dependent Granule to External Membrane Protein (PADGEM). It was first identified in endothelial cells in 1989.
Gene and regulation
P-selectin is located on chromosome 1q21-q24, spans > 50 kb and contains 17 exons in humans. P-selectin is constitutively expressed in megakaryocytes (the precursor of platelets) and endothelial cells. P-selectin expression is induced by two distinct mechanisms. First, P-selectin is synthesized by megakaryocytes and endothelial cells, where it is sorted into the membranes of secretory granules. When megakaryocytes and endothelial cells are activated by agonists such as thrombin, P-selectin is rapidly translocated to the plasma membrane from granules. Secondly, increased levels of P-selectin mRNA and protein are induced by inflammatory mediators such as tumor necrosis factor-a (TNF-a), LPS, and interleukin-4 (IL-4). Although TNF-a and LPS increase levels of both mRNA and protein in murine models, they do not appear to affect mRNA in human endothelial cells, while IL-4 increases P-selectin transcription in both species. The elevated synthesis of P-selectin may play an important role in the delivery of protein to the cell surface. In ischemic stroke patients, plasma P-selectin concentration was reported to be highly correlated to plasminogen activator inhibitor-1 activity and tissue plasminogen activator activity.
Mixed train
A mixed train is a train that hauls both passenger and freight cars or wagons. In the early days of railways they were quite common, but by the 20th century they were largely confined to branch lines with little traffic. Because mixed trains involve the shunting of goods wagons at stations along the way, they provide passengers with a very slow service, and have largely disappeared today. Their use is also at variance with the separation of passenger and goods services into different subsidiaries by most modern railway administrations.
Africa and Asia
In parts of Asia and Africa, mixed trains are still the norm on routes with little traffic.
Australia
In Australia, mixed trains could also be called a "car goods", "goods train with car attached", or "mixed goods". This last term could cause confusion, as "mixed goods" in some other countries can refer to a freight train carrying multiple types of freight rather than just one commodity. In most states, a mixed train was technically a goods train with passenger accommodation, meaning it had lower priority over other trains and could be cancelled without notice if there was no goods to carry.
Podcasts:
Godlike Music Port
ALBUMS
- Future Trance, Volume 55 released: 2011
- Diamonds & Pearls Lounge Vol. 2 released: 2009
Future Trance, Volume 55
Released 2011- Till Morning (Dan Winter remix edit)
- Yeah Yeah Yeah (Ryan T. & Rick M. Bootleg radio edit)
- Who's That Chick (G4bby feat. Bazz Boyz remix edit)
- Everytime (Cc.K Meets Rocco remix)
- Supernatural
- Upside Down
- Party Doesn't Stop
- Heartbreaker
- Can't Stop Love (Crystal Lake remix edit)
- You Take Me Away
- Reviens-Moi (Empyre One remix edit)
- Pump It Up (Monday 2 Friday remix edit)
- Burn This City
- Turn Back Time
- Lost Without a Fight
- Out of Town (Ti-Mo remix edit)
- Forever Is Over (Giorno radio edit)
- Lift Me Up (G4bby feat. Bazz Boyz remix edit)
- Follow Me Tonight
- Forever Loved
- 2 Times 2K11 (Klubbingman vs. Steve Buzz edit)
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by Quimby
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Here's Where I Stand
by: CampHere in the dark
I stand before you
Knowing this is my chance to show you my heart
This is the start
This is the start
I have so much to say and I'm hopin'
That your arms are open
Don't turn away, I want you near me
But you have to hear me
Here's where I stand
Here's who I am
Love me, but don't tell me who I have to be
Here's who I am, I'm what you see
You said I had to change and I was tryin'
But my heart was lyin'
I'm not that child any longer
I am stronger
Here's where I stand
Here's who I am
Help me to move on but please don't tell me how
I'm on my way, I'm movin' now
In this life we've come so far
But we're only who we are
With the courage of love
To show us the way
We've got the power to stand up and say
Here's where I stand
Here's where I am
Stand up and be counted, I'm counting on you
If you're with me
We'll make it through
Here's where I stand
Here's who I am
Love me, love me, love me and we'll make it through
Here's where I stand
Baby, baby, baby I'm counting on you
Here's where I stand
Love me, love me, love me and we'll make it through
I'm counting
I'm counting
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The Times of India 21 Mar 2025- 1
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