Glutamine (abbreviated as Gln or Q; encoded by the codons CAA and CAG) is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated -+NH3 form under biological conditions), an α-carboxylic acid group (which is in the deprotonated –COO- form under biological conditions), and a side chain amide which replaces the side chain hydroxyl of glutamic acid with an amine functional group, classifying it as a charge neutral, polar (at physiological pH) amino acid. It is non-essential and conditionally essential in humans, meaning the body can usually synthesize sufficient amounts of it, but in some instances of stress, the body's demand for glutamine increases and glutamine must be obtained from the diet.
In human blood, glutamine is the most abundant free amino acid, with a concentration of about 500–900 µmol/l.
Glutamine plays a role in a variety of biochemical functions:
There is a house in New Orleans
They call the Rising Sun
And it's been the ruin of many a poor boy
And God I know I'm one
My mother was a tailor
She sewed my new bluejeans
My father was a gamblin' man
Down in New Orleans
Now the only thing a gambler needs
Is a suitcase and trunk
And the only time he's satisfied
Is when he's on a drunk
Oh mother tell your children
Not to do what I have done
Spend your lives in sin and misery
In the House of the Rising Sun
Well, I got one foot on the platform
The other foot on the train
I'm goin' back to New Orleans
To wear that ball and chain
Well, there is a house in New Orleans
They call the Rising Sun
And it's been the ruin of many a poor boy