Blaufränkisch

Blaufränkisch (German for blue Frankish) is a dark-skinned variety of grape used for red wine. Blaufränkisch, which is a late-ripening variety, produces red wines which are typically rich in tannin and may exhibit a pronounced spicy character.

The grape is grown across Central Europe, including Austria, Czech Republic (in particular southern Moravia where it is known as Frankovka), Germany, Slovakia (where it is known as Frankovka modrá), Croatia (frankovka), Slovenia (known as modra frankinja), and Italy (Franconia). In Hungary the grape is called Kékfrankos (also lit. blue Frankish) and is grown in a number of wine regions including Sopron, Villány, Szekszárd, and Eger (where it is a major ingredient in the famous red wine blend known as Egri Bikavér (lit. Bull's Blood) having largely replaced the Kadarka grape). It has been called "the Pinot noir of the East" because of its spread and reputation in Eastern Europe. In America this grape is grown in Idaho, Washington State and the Finger Lakes region of New York State, where like in Germany it is known as Lemberger, Blauer Limberger or Blue Limberger.

Game (2014 film)

Game is a 2014 action thriller Bengali film choreographed and directed by Baba Yadav and produced and distributed by Reliance Entertainment. The film features actors Jeet and Subhasree Ganguly in the lead roles. Music of the film has been composed by Jeet Ganguly.The film is a remake of the 2012 Tamil film Thuppakki starring Vijay and Kajal Aggarwal in the Lead roles. It is also remade in Hindi named Holiday.

Plot

Abhimanyu Chatterjee (Jeet), a Captain in the Indian Army, returns to Kolkata from Kashmir. On his arrival, his parents and younger sisters force him to see Trisha (Subhashree Ganguly), who they choose for him to be married to. At the bride-viewing ceremony, Abhimanyu makes up excuses to avoid marrying her, which includes commenting about her being old-fashioned. On the contrary, Trisha is a college-level boxer, who is completely modern in her outlook. Abhimanyu realises this and proposes to her, which she reciprocates.

One day, while travelling around the city with his police officer-friend Santilal, Abhimanyu witnesses the explosion of a bus in which they had travelled. He manages to capture the man who laid the bomb, but he escapes from the hospital where he was kept under custody. kidnaps the bomber again, and also forces the police officer who helped the bomber's escape, to commit suicide. Abhimanyu soon learns that the bomber is a mere executor, a sleeper cell, whose only role was to plant the bomb. He also discovers that the Islamic terrorist group Harkat-ul-Jihad al-Islami, which the bomber belongs to, has planned various such attacks in the city in a couple of days. Enlisting the help of his fellow Army men and Balaji, Jagadish manages to thwart these attacks and kill the sleeper cell leader's brother and eleven other terrorists, including the first sleeper cell.

Game (2006 film)

Game (Telugu: గేమ్) is a Telugu film that released on 5 August 2006 and was directed by Ram Prasad. It stars Mohan Babu and Vishnu Manchu in lead roles with Shobana, Parvati Melton, Sumalatha and Giri Babu in supporting roles. The film's background score and soundtrack were composed by new age music composer, Joshua Sridhar. The soundtrack for the movie was released on 27 July 2006. The movie is based on Hollywood Movie Changing Lanes which was remade in three Indian languages, Taxi No. 9211 (2006) in Hindi, TN-07 AL 4777 (2009) in Tamil and this movie itself in Telugu. Unlike the previous versions, Game received negative reviews and failed at the box-office.

Cast

External links

2015 Rugby Championship

The 2015 Rugby Championship was the fourth edition of the expanded annual southern hemisphere Rugby Championship consisting of Argentina, Australia, South Africa and New Zealand.

The 2015 Championship was a shorter competition than normal, with each team playing each other once, rather than twice (home and away). This was so that teams had a longer preparation time ahead of the 2015 Rugby World Cup which started on 18 September. However, New Zealand hosted an additional match against Australia in Auckland on 15 August which acted as the second Bledisloe Cup test and as a World Cup warm-up. Argentina hosted a second match against South Africa on the same date.

The tournament was known for sponsorship reasons as The Castle Rugby Championship in South Africa, The Investec Rugby Championship in New Zealand, The Castrol Edge Rugby Championship in Australia and The Personal Rugby Championship in Argentina.

Australia won the Championship, becoming just the second team to win the tournament since 2012. However, including the previous format of the Championship, Australia claimed the title for the first time since 2011, and achieved a 100% win rate for the first time ever in either format.

Endoglin

Endoglin (ENG) is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. It is also commonly referred to as CD105, END, FLJ41744, HHT1, ORW and ORW1. It has a crucial role in angiogenesis, therefore, making it an important protein for tumor growth, survival and metastasis of cancer cells to other locations in the body.

Gene and expression

The human endoglin gene is located on human chromosome 9 with location of the cytogenic band at 9q34.11. Endoglin glycoprotein is encoded by 39,757 bp and translates into 658 amino acids.

The expression of the endoglin gene is usually low in resting endothelial cells. This, however, changes once neoangiogenesis begins and endothelial cells become active in places like tumor vessels, inflamed tissues, skin with psoriasis, vascular injury and during embryogenesis. The expression of the vascular system begins at about 4 weeks and continues after that. Other cells in which endoglin is expressed consist of monocytes, especially those transitioning into macrophages, low expression in normal smooth muscle cells, high expression vascular smooth muscle cells and in kidney and liver tissues undergoing fibrosis.