Gabre

Gabre is a commune in the Ariège department in southwestern France.

Geography

The Lèze, with the Lake of Mondely, forms part of the commune's southeastern border, flows northeast through the eastern part of the commune, then forms part of its northeastern border.

Population

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GABRE

Gamma-aminobutyric acid receptor subunit epsilon is a protein that in humans is encoded by the GABRE gene.

The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants encoding different isoforms have been identified.

Brainstem expression of ε subunit-containing GABA_A receptors is upregulated during pregnancy, particularly in the ventral respiratory group.

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.