GRP

GRP may refer to:

Biochemistry

  • Gastrin Releasing Peptide
  • Glucose-regulated protein
  • Grape reaction product, a phenolic compound found in aged red wines

    • Computing

  • Gentoo Reference Platform, pre-compiled packages for Gentoo Linux
  • .grp file extension
  • Program Manager folder format
  • Build engine data format
  • StarCraft graphics file format
  • grp.h, C header file defined by IEEE Std 1003.1 to provide group structure

    • Technology

  • Government Resource Planning, GRP is software designed for the unique requirements of public financial management. GRP software is budget-driven through the use of Commitment Accounting, where the budget is the legal embodiment of government objectives. Commitment Accounting is used only in government and other forms of public financial management.
  • Glass Reinforced Plastic, also known as fiberglass.

    • Other

  • Gross Regional Product
  • Gibraltar Reform Party
  • Gross Rating Point, a term used in advertising on the television
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    This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/GRP

    Gastrin-releasing peptide

    Gastrin-releasing peptide, also known as GRP, is a neuropeptide, a regulatory molecule that has been implicated in a number of physiological and pathophysiological processes. Most notably, GRP stimulates the release of Gastrin from the G cells of the stomach.

    The gene from which GRP is derived encodes a number of bombesin-like peptides. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.

    Function

    Gastrin-releasing peptide is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. The post-ganglionic fibers of the vagus nerve that innervate the G cells of the stomach release GRP, which stimulates the G cells to release gastrin.

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    This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/Gastrin-releasing_peptide

    HSP90B1

    Heat shock protein 90kDa beta member 1 (HSP90B1), known also as endoplasmin, gp96, grp94 and ERp99, is a chaperone protein that in humans is encoded by the HSP90B1 gene.

    HSP90B1 is an HSP90 paralogue that is found in the endoplasmic reticulum. It plays critical roles in folding proteins in the secretory pathway such as Toll-like receptors and integrins. It has been implicated as an essential immune chaperone to regulate both innate and adaptive immunity. Tumor-derived HSP90B1 (vitespen) has entered clinical trials for cancer immunotherapy.

    References

    Further reading


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    This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/HSP90B1

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