GPR101
Probable G-protein coupled receptor 101 is a protein that in humans is encoded by the GPR101 gene.
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.
Clinical significance
A duplication event in GPR101 is implicated in cases of gigantism and acromegaly.
References
Further reading
Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878.