Guanine nucleotide-binding protein subunit beta-5 is a protein that in humans is encoded by the GNB5 gene. Alternatively spliced transcript variants encoding different isoforms exist.
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.
GNB5 has been shown to differentially control RGS protein stability and membrane anchor binding, and therefore is involved in the control of complex neuronal G protein signaling pathways.
GNB5 has been shown to interact with:
The lights were low but I was lower
The radio was playing somewhere else
The room was full of surface tension
I was only thinking ‘bout myself
No baby I
No baby I
No baby I don’t want to see you hurt
You got them tears they fall like pearls
Blame it on gravity, yeah
Blame it on being a girl
The room was full of undertakers
Movers and martini shakers gone
The reaper left at 7:30
Took off in a taxi with a blonde
The difference between us
Is way down on the inside
It’s very tricky business
No baby I
No baby I
No baby I don’t want to see you hurt
You got them tears
They fall like pearls
Blame it on gravity, yeah
Blame it on being a girl
Blame it on gravity, yeah
Blame it on being a girl
Here’s a toast to no good Friday
I was bound to do it my way wrong
Strum it on a telecaster
Sing it like a train disaster song
The difference between us
Is way down on the inside
And it’s very tricky business
No baby I
No baby I
No baby I don’t want to see you hurt
You got them tears they fall like pearls
Blame it on gravity, yeah
Blame it on being a girl
Blame it on gravity, yeah