GLE may refer to:
Nucleoporin GLE1 is a protein that in humans is encoded by the GLE1 gene on chromosome 9.
This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
A genome-wide screening and linkage analysis assigned the disease locus of lethal congenital contracture syndrome, one of 40 Finnish heritage diseases, to a defined region of 9q34, where the GLE1 gene is located. Mutations in GLEI have been identified in families with foetal motoneuron disease.
I just hung up the phone
I was talking to you
We said good bye
I sat down and cry
Coz' I remembered the things
That we've done
When we were sitting together
And our love has begun
For more and more
I want to go back in time
I'll always love you
I hope you know
But on and on
I need to wait
Chorus:
7 1/2 years that was our pact
7 1/2 years there is no turning back
7 1/2 years till I get to see you again
I am looking at the pictures
Of me and you
Both of us were smiling
For this damn photo-shoot
That was the day when it all began
But all I want to now
Is to see you again
For more and more
I want to go back in time
I'll always love you
I hope you know
But on and on
I need to wait