G-130
G-130 (GP-130, 2-Phenyl-5,5-dimethyltetrahydro-1,4-oxazine) is a drug with stimulant and anorectic effects, related to phenmetrazine.
Structural analogs
Compounds related to G 130 and radafaxine were synthesized that behave as combined inhibitors of monoamine uptake and nAChRs.
See also
2-Phenyl-3,6-dimethylmorpholine
3-Fluorophenmetrazine
Phendimetrazine (2-Phenyl-3,4-dimethylmorpholine)
Manifaxine
Radafaxine
References
↑ GB 1336732 - Diethanolamine Derivatives.
↑ Fanelli O (June 1973). "Pharmacological and toxicological study of a new psychotropic stimulant: the 2-phenyl-5-dimethyl-tetrahydro-1,4-oxazine, in comparison with d,l-amphetamine, phenmetrazine and pemoline-Mg". Arzneimittel-Forschung 23 (6): 810–6. PMID 4740767.
↑ Fanelli O, Mazzoncini V, Ferri S (October 1974). "Toxicological and teratological study of 2-phenyl-5,5-dimethyl-tetrahydro-1,4-oxazine hydrochloride (G 130), a psychostimulant drug". Arzneimittel-Forschung 24 (10): 1627–32. PMID 4479774.
↑ Fanelli O, Mazzoncini V, Trallori L (December 1974). "Antagonism of psychostimulant 2-phenyl-5,5-dimethyl-tetrahydro-1,4-oxazine hydrochloride (G 130) to central nervous system depressing drugs. Monoamine oxidase inhibitory activity and norepinephrine and serotonin induced changes. Comparison with dL-amphetamine". Arzneimittel-Forschung 24 (12): 2025–9. PMID 4480283.