Paper Mate
Paper Mate is a registered division of Sanford L.P., a Newell Rubbermaid company that produces writing instruments. Paper Mate's offices are located in Oak Brook, Illinois along with those of Newell Rubbermaid's other office products divisions.
History
Early in 1941 Patrick J. Frawley acquired his first company, a ballpoint pen parts manufacturer that had defaulted on its loan. In 1949, The Frawley Pen Company developed a revolutionary new ink, which dried instantly. The pen that delivered this ink was called "The Paper Mate".
In 1955 the Frawley Pen Company was acquired by Gillette for $15.5 million. In late 2000, Gillette's stationery products division was purchased by Newell Rubbermaid.
Products
Paper Mate manufactures ballpoint pens, mechanical pencils, Flair felt tip pens, and erasers, which are offered in a wide variety of colors and shapes. In 2010, Paper Mate introduced environmentally friendly biodegradeable pens, pencils and erasers as additions to its wide-ranging product portfolio.
Fluid-attenuated inversion recovery
Summary
Fluid-attenuated inversion recovery (FLAIR) is a pulse sequence used in magnetic resonance imaging which was invented by Dr. Graeme Bydder. FLAIR can be used with both three-dimensional imaging (3D FLAIR) or two dimensional imaging (2D FLAIR).
The pulse sequence is an inversion recovery technique that nulls fluids. For example, it can be used in brain imaging to suppress cerebrospinal fluid (CSF) effects on the image, so as to bring out the periventricular hyperintense lesions, such as multiple sclerosis (MS) plaques.
By carefully choosing the inversion time (TI), the signal from any particular tissue can be nulled. The appropriate TI depends on the tissue via the formula:
in other words, one should typically use a TI of around 70% of the T1 value. In the case of CSF suppression, one aims for T2 weighted images. Therefore, if the long T1 (inversion time) is adjusted to a zero crossing point, the signal of the CSF is theoretically being "erased," from the derived image.
Flamingo
Flamingos or flamingoes/fləˈmɪŋɡoʊz/ are a type of wading bird in the genus Phoenicopterus, the only genus in the family Phoenicopteridae. There are four flamingo species in the Americas and two species in the Old World.
Etymology
Flamingo comes from Spanish flamenco, "with the colour of flame", in turn coming from Provençal flamenc from flama "flame" and Germanic-like suffix -ing, with a possible influence of words like Fleming. A similar etymology has the Latinate Greek term Phoenicopterus (from Greek: φοινικόπτερος phoinikopteros), literally "blood red-feathered".
Taxonomy and systematics
Traditionally, the long-legged Ciconiiformes, probably a paraphyletic assemblage, have been considered the flamingos' closest relatives and the family was included in the order. Usually the ibises and spoonbills of the Threskiornithidae were considered their closest relatives within this order. Earlier genetic studies, such as those of Charles Sibley and colleagues, also supported this relationship. Relationships to the waterfowl were considered as well, especially as flamingos are parasitized by feather lice of the genus Anaticola, which are otherwise exclusively found on ducks and geese. The peculiar presbyornithids were used to argue for a close relationship between flamingos, waterfowl, and waders. A 2002 paper concluded they are waterfowl, but a 2014 comprehensive study of bird orders found that flamingos and grebes are not waterfowl, but rather are part of Columbea along with doves, sandgrouse, and mesites.
Flamingo (protein)
Flamingo is a member of the adhesion-GPCR family of proteins. Flamingo has sequence homology to cadherins and G protein-coupled receptors (GPCR). Flamingo was originally identified as a Drosophila protein involved in planar cell polarity. Mammals have three flamingo homologs, CELSR1, CELSR2, CELSR3. In mice all three have distinct expression patterns in the brain.
Adhesion G protein coupled receptors
The adhesion-GPCR family has over thirty members in the human genome. The adhesion GPCRs are seven transmembrane helix proteins that have long N-terminal domains. For example, flamingo has EGF-like, Laminin G-like and Cadherin-like sequences in its N-terminal extracellular domain.
Axon fascicles
Mice that lack CELSR3 have altered bundeling of axons to form fascicles.
Function in dendrite morphology
In Drosophila, flamingo mutants were found to have abnormal dendrite branching, outgrowth and routing. Kimura et al. proposed that flamingo regulates dendrite branch elongation and prevents the dendritic trees of adjacent Drosophila sensory neurons from having overlap of dendritic arbors.
Flamingo (Brandon Flowers album)
Flamingo is the debut solo studio album by American singer-songwriter and the Killers frontman Brandon Flowers, released on September 3, 2010 by Island Records. It was recorded at Battle Born Studios, Winchester, Nevada, and Henson Recording Studios, Hollywood, California. The album debuted at number one on the UK Albums Chart.
Background
After a mysterious countdown on the Killers official website, Flowers confirmed on April 29, 2010 that he would be releasing a solo album entitled Flamingo. The album is named after Flamingo Road (in Brandon's hometown of Las Vegas), where many pivotal events in his life occurred: Sam's Town Casino is on Flamingo, his first job was at a golf course on that road, and he met his wife in a thrift store on the road as well.
Track "Welcome to Fabulous Las Vegas" references the Las Vegas Boulevard ("The Strip"). Track "Was It Something I Said?" references Tropicana Avenue and a job at the Golden Nugget Las Vegas located on the Freemont Street Experience. Track "Magdalena" references a 50 mile pilgrimage from Nogales, Sonora to Magdalena, Sonora in Mexico.
Podcasts:
