Fire

Fire is the rapid oxidation of a material in the exothermic chemical process of combustion, releasing heat, light, and various reaction products. Slower oxidative processes like rusting or digestion are not included by this definition.

Fire is hot because conversion of the weak double bond in molecular oxygen, O₂, to the stronger bonds in the combustion products carbon dioxide and water releases energy (418 kJ per 32 g of O₂); the bond energies of the fuel play only a minor role here. At a certain point in the combustion reaction, called the ignition point, flames are produced. The flame is the visible portion of the fire. Flames consist primarily of carbon dioxide, water vapor, oxygen and nitrogen. If hot enough, the gases may become ionized to produce plasma. Depending on the substances alight, and any impurities outside, the color of the flame and the fire's intensity will be different.

Fire in its most common form can result in conflagration, which has the potential to cause physical damage through burning. Fire is an important process that affects ecological systems around the globe. The positive effects of fire include stimulating growth and maintaining various ecological systems. Fire has been used by humans for cooking, generating heat, light, signaling, and propulsion purposes. The negative effects of fire include hazard to life and property, atmospheric pollution, and water contamination. If fire removes protective vegetation, heavy rainfall may lead to an increase in soil erosion by water. Also, when vegetation is burned, the nitrogen it contains is released into the atmosphere, unlike elements such as potassium and phosphorus which remain in the ash and are quickly recycled into the soil. This loss of nitrogen caused by a fire produces a long-term reduction in the fertility of the soil, which only slowly recovers as nitrogen is "fixed" from the atmosphere by lightning and by leguminous plants such as clover.

Fire!!

Fire!! was an African-American literary magazine published in New York City in 1926 during the Harlem Renaissance. The publication was started by Wallace Thurman, Zora Neale Hurston, Aaron Douglas, John P. Davis, Richard Bruce Nugent, Gwendolyn Bennett, Lewis Grandison Alexander, Countee Cullen, and Langston Hughes. After it published one issue, its quarters burned down, and the magazine ended.

History

Fire!! was conceived to express the African-American experience during the Harlem Renaissance in a modern and realistic fashion, using literature as a vehicle of enlightenment. The magazine's founders wanted to express the changing attitudes of younger African Americans. In Fire!! they explored edgy issues in the Black community, such as homosexuality, bisexuality, interracial relationships, promiscuity, prostitution, and color prejudice.

Langston Hughes wrote that the name was intended to symbolize their goal "to burn up a lot of the old, dead conventional Negro-white ideas of the past ... into a realization of the existence of the younger Negro writers and artists, and provide us with an outlet for publication not available in the limited pages of the small Negro magazines then existing.". The magazine's headquarters burned to the ground shortly after it published its first issue. It ended operations.

Fire (disambiguation)

Fire is the rapid oxidation of a material in the chemical process of combustion.

Fire may also refer to:

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Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase

Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase (EC 3.1.3.86, SHIP1, SHIP2, SHIP, p150Ship) is an enzyme with system name 1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase. This enzyme catalyses the following chemical reaction

This enzyme hydroylses 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2.

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INPP5D

Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 is an enzyme that in humans is encoded by the INPP5D gene. INPP5D also called SHIP1 was also shown to be a negative regulator of BCR signalling in B cells.

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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