Fenarimol

Fenarimol, sold under the tradenames Bloc, Rimidin and Rubigan, is a fungicide which acts against rusts, blackspot and mildew fungi. It is used on ornamental plants, trees, lawns, tomatoes, peppers, eggplants, cucumbers and melons. It is mainly used to control powdery mildew. It works by inhibiting the fungus's biosynthesis of important steroid molecules.

Description

Fenarimol was developed by Eli Lilly & Company around 1971.

Fenarimol can lead to increased growth of MCF7 breast cancer cells. It has been found to be an endocrine disruptor, acting as a xenoestrogen and antiandrogen.

Synthesis

Fenarimol is made by the reaction of a diarylketon with an organolithium derived by halogen-metal exchange.

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