Factor D

Factor D (EC 3.4.21.46, C3 proactivator convertase, properdin factor D esterase, factor D (complement), complement factor D, CFD, adipsin) a protein which in humans is encoded by the CFD gene. Factor D is involved in the alternative complement pathway of the complement system where it cleaves factor B.

Function

The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.

Factor D is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis.

Clinical significance

The level of Factor D is elevated in the obese, this elevation may be due to high activity or resistance but exact cause is not totally known.

Factor

Factor, a Latin word meaning "who/which acts", may refer to:

Commerce

Science and technology

Biology

Computer science and information technology

Factor (programming language)

Factor is a stack-oriented programming language created by Slava Pestov. Factor is dynamically typed and has automatic memory management, as well as powerful metaprogramming features. The language has a single implementation featuring a self-hosted optimizing compiler and an interactive development environment. The Factor distribution includes a large standard library.

History

Slava Pestov created Factor in 2003 as a scripting language for a video game. The initial implementation, now referred to as JFactor, was implemented in Java and ran on the Java Virtual Machine. Though the early language resembled modern Factor superficially in terms of syntax, the modern language is very different in practical terms and the current implementation is much faster.

The language has changed significantly over time. Originally, Factor programs centered on manipulating Java objects with Java's reflection capabilities. From the beginning, the design philosophy has been to modify the language to suit programs written in it. As the Factor implementation and standard libraries grew more detailed, the need for certain language features became clear, and they were added. JFactor did not have an object system where you could define your own classes, and early versions of native Factor were the same; the language was similar to Scheme in this way. Today, the object system is a central part of Factor. Other important language features such as tuple classes, combinator inlining, macros, user-defined parsing words and the modern vocabulary system were only added in a piecemeal fashion as their utility became clear.

Factoring (finance)

Factoring is a financial transaction and a type of debtor finance in which a business sells its accounts receivable (i.e., invoices) to a third party (called a factor) at a discount. A business will sometimes factor its receivable assets to meet its present and immediate cash needs.Forfaiting is a factoring arrangement used in international trade finance by exporters who wish to sell their receivables to a forfaiter. Factoring is commonly referred to as accounts receivable factoring, invoice factoring, and sometimes accounts receivable financing. Accounts receivable financing is a term more accurately used to describe a form of asset based lending against accounts receivable.

Factoring is not the same as invoice discounting (which is called an "Assignment of Accounts Receivable" in American accounting – as propagated by FASB within GAAP). Factoring is the sale of receivables, whereas invoice discounting ("assignment of accounts receivable" in American accounting) is a borrowing that involves the use of the accounts receivable assets as collateral for the loan. However, in some other markets, such as the UK, invoice discounting is considered to be a form of factoring, involving the "assignment of receivables", that is included in official factoring statistics. It is therefore also not considered to be borrowing in the UK. In the UK the arrangement is usually confidential in that the debtor is not notified of the assignment of the receivable and the seller of the receivable collects the debt on behalf of the factor. In the UK, the main difference between factoring and invoice discounting is confidentiality.