In law, a question of fact, also known as a point of fact, is a question which must be answered by reference to facts and evidence, and inferences arising from those facts. Such a question is distinct from a question of law, which must be answered by applying relevant legal principles. The answer to a question of fact (a "finding of fact") is usually dependent on particular circumstances or factual situations.
To illustrate the difference:
After hearing evidence, a U.S. court may issue a "Findings of Fact and Conclusions of Law," which separately examines the factual issues and then draws a legal conclusion. In the above example, the court might write that the facts have been established to a required standard of proof that Mr. and Mrs. Jones left their 10 year old child home alone with a baby for several days. The conclusion of law would then follow, outlining the given child neglect statute that Mr. and Mrs. Jones violated.
FACT (facilitates chromatin transcription) is a heterodimeric protein complex that affects eukaryotic RNA polymerase II (Pol II) transcription elongation both in vitro and in vivo. It was discovered in 1998 as a factor purified from human cells that was essential for productive in vitro Pol II transcription on a chromatinized DNA template.
FACT consists of 140 and 80 kilodalton (kDa) subunits. The 140 kDa subunit is encoded by a human gene (SUPT16H) which is 36% identical to the S. cerevisiae gene Spt16 and the 80 kDa subunit is human SSRP1 (POB3 in S. cerevisiae). Both of these subunits in yeast affect Pol II transcription elongation, and purified human FACT binds specifically to mononucleosomes and the histone H2A/H2B dimer, but not to the H3/H4 tetramer (see: Nucleosome core particle) or Pol II.
Co-immunoprecipitation assays with tagged recombinant proteins showed that the Spt16 subunit interacts with H2A/H2B dimers and mononucleosomes, but not H3/H4 tetramers, whereas the SSRP1 subunit interacts only with H3/H4 tetramers and not mononucleosomes. Deletion of the highly acidic carboxy-terminus of Spt16 (a common feature of known histone chaperones) does not prevent Spt16 from forming a stable complex with SSRP1, but it does eliminate interaction with mononucleosomes and ability to stimulate in vitro transcription on chromatinized templates. The two subunits together, but neither alone, can stimulate formation of nucleosomes from free histones and DNA (histone chaperone activity). These two subunits are highly conserved across all eukaryotes, and in addition to transcription, have been shown to affect DNA repair and replication as well.
Fact 2002 was a 12 inch record released by the pop group Bis, paying tribute to Factory Records. The EP was given a low-key release.
It features covers of Joy Division's biggest hit "Love Will Tear Us Apart" (1980), New Order's B-side "Hurt" which was released with "Temptation" (1982), the debut single of A Certain Ratio "Shack Up" (1980) and "Looking from a Hilltop" from Section 25, which originally appeared on From the Hip (1984).
Mix, mixes, mixture, or mixing may refer to:
A DJ mix or DJ mixset is a sequence of musical tracks typically mixed together to appear as one continuous track. DJ mixes are usually performed using a DJ mixer and multiple sounds sources, such as turntables, CD players, digital audio players or computer sound cards, sometimes with the addition of samplers and effects units, although it's possible to create one using sound editing software.
DJ mixing is significantly different from live sound mixing. Remix services were offered beginning in the late 1970s in order to provide music which was more easily beatmixed by DJs for the dancefloor. One of the earliest DJs to refine their mixing skills was DJ Kool Herc.Francis Grasso was the first DJ to use headphones and a basic form of mixing at the New York nightclub Sanctuary. Upon its release in 2000, Paul Oakenfold's Perfecto Presents: Another World became the biggest selling dj mix album in the US.
A DJ mix is often put together with music from genres that fit into the more general term electronic dance music. Other genres mixed by DJ includes hip hop, breakbeat and disco. Four on the floor disco beats can be used to create seamless mixes so as to keep dancers locked to the dancefloor. Two of main characteristics of music used in dj mixes is a dominant bassline and repetitive beats. Music mixed by djs usually has a tempo which ranges from 120 bpm up to 160 bpm.
Audio mixing is the process by which multiple sounds are combined into one or more channels. In the process, the source signals' level, frequency content, dynamics, and panoramic position are manipulated and effects such as reverb may be added. This practical, aesthetic, or otherwise creative treatment is done in order to produce a mix that is more appealing to listeners.
Audio mixing is practiced for music, film, television and live sound. The process is generally carried out by a mixing engineer operating a mixing console or digital audio workstation.
Before the introduction of multitrack recording, all the sounds and effects that were to be part of a recording were mixed together at one time during a live performance. If the mix wasn't satisfactory, or if one musician made a mistake, the selection had to be performed over until the desired balance and performance was obtained. However, with the introduction of multitrack recording, the production phase of a modern recording has radically changed into one that generally involves three stages: recording, overdubbing, and mixdown.
When I think of all I put you through
Always taking you for granted
I never saw it from your point of view
Blinded by the double standard
You were tryin' to tell me all along
Something in the love was missing
You said "It's not too late to get it back"
But I just wasn't listening
If I knew back then what I know now
If I understood the what , when , why and how
Now it's clear to me
What I should have done
But hindsight is 20/20 vision
Now I see it in a different light
I've been losin' you in stages
Give us one more chance
I'll get it right
Girl , you're gonna see some changes
If I knew back then what I know now
If i understood the what , when , why and how
Now it's clear to me
What I should have done
But hindsight is 20/20 vision
Takin' time to catch up on some history
Tryin' to figure out what went wrong
with you and me
And it doesn't really matter
what's been before
But I know there's no future
with you walkin' out that door