N-formyl peptide receptor 3 (FPR3) is a receptor protein that in humans is encoded by the FPR3 gene.
Confusingly, there are two nomenclatures for FPR receptors and their genes, the first one used, FPR, FPR1, and FPR2 and its replacement (which corresponds directly to these three respective receptors and their genes), FPR1, FPR2, and FPR3. The latter nomenclature is recommended by the International Union of Basic and Clinical Pharmacology and is used here. Other previously used names for FPR1 are NFPR, and FMLPR; for FPR2 are FPRH1, FPRL1, RFP, LXA4R, ALXR, FPR2/ALX, HM63, FMLPX, and FPR2A; and for FPR3 are FPRH2, FPRL2, and FMLPY.
The overall function of FPR3 is quite unclear. Compared to FPR1 and FPR2, FPR3 is highly phosphorylated (a signal for receptor inactivation and internalization) and more localized to small intracellular vesicles. This suggests that FPR3 rapidly internalizes after binding its ligands and thereby may serve as a "decoy" receptor to reduce the binding of its ligands to FRP1 and FRP2 receptors.
I threw your keys in the water, I looked back,
Theyd frozen halfway down in the ice.
They froze up so quickly, the keys and their owners,
Even after the anger, it all turned silent, and
The everyday turned solitary,
So we came to February.
First we forgot where wed planted those bulbs last year,
Then we forgot that wed planted at all,
Then we forgot what plants are altogether,
and I blamed you for my freezing and forgetting and
The nights were long and cold and scary,
Can we live through February?
You know I think Christmas was a long red glare,
Shot up like a warning, we gave presents without cards,
And then the snow,
And then the snow came, we were always out shoveling,
And wed drop to sleep exhausted,
Then wed wake up, and its snowing.
And February was so long that it lasted into March
And found us walking a path alone together.
You stopped and pointed and you said, "Thats a crocus,"
And I said, "Whats a crocus?" and you said, "Its a flower,"
I tried to remember, but I said, "Whats a flower?"
You said, "I still love you."
The leaves were turning as we drove to the hardware store,
My new lover made me keys to the house,
And when we got home, well we just started chopping wood,
Because you never know how next year will be,
And well gather all our arms can carry,