Forkhead box protein E1 is a protein that in humans is encoded by the FOXE1 gene.
The FOXE1 gene is located on the long (q) arm of chromosome 9 at position 22 FOXE1
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis.
Mutations in this gene cause Bamforth-Lazarus syndrome and are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.
The region surrounding the FOXE1 gene has shown association in the pathogenesis of cleft lip and palate with genome-wide levels of significance in linkage analysis studies with additional fine-mapping and replication.
FOXE1 is expressed transiently in the developing thyroid and the anterior pituitary gland.
A little kid goes from
size one to size two
still we have same job
what is it that we do
all the change that's going on
in that tiny mind
still we're indecisive,
still we're wasting time
and there's cause, cause,
cause to be alarmed
who feeds the dove
who gives the world its charm
cause, cause, cause to be alarmed
we are pumped up fantasies
until the world's disarmed
a little hungry face
deserved more than roots to chew
they will erupt "enough's enough"
they'll lay the blame on you
and these perceiving minds observe
to count the final score
no treasure chest, to reinvest
just a bunch of whores
and there is cause, cause,
cause to be alarmed
no making love
until the world's disarmed
cause, cause, cause to be alarmed
a frigid little fantasy
until the world's disarmed
fly bird high bird
a love bird got shot
heard the lead bird's a dead bird
a new mind goes from birth,
to full view to old fool
still we have the same face
just what do we achieve?
all these minds that think alike
do damage to the strain
where we stand the very spot
we will not stand again
and there is cause, cause,
cause to be alarmed
who feeds the dove
who gives the world its charm
cause, cause, cause to be alarmed
we are pumped up fantasies
until the world is disarmed
fly bird high bird
go see bird and tell bird
that a love bird got shot,