FHIT
Bis(5'-adenosyl)-triphosphatase also known as fragile histidine triad protein (FHIT) is an enzyme that in humans is encoded by the FHIT gene.
Function
FHIT is also known as human accelerated region 10. It may, therefore, have played a key role in differentiating humans from apes.
This gene, a member of the histidine triad gene family, encodes a diadenosine P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas.
Though the exact molecular function of FHIT is still partially unclear, the gene works as a tumor suppressor as it has been demonstrated in animal studies. Furthermore FHIT has been shown to synergize with VHL, another tumor suppressor, in protecting against chemically - induced lung cancer.
Podcasts:
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by Foghat
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by Foghat
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by Foghat
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by Foghat
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by Foghat
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by Foghat
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by Foghat
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by Foghat
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by Veda
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by Veda
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by Veda
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by Veda
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by Veda
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by Veda
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by Veda
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by Veda
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by Veda
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by Veda
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by Veda
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by Veda
Ain't Livin' Long Like This
by: FoghatR. Crowell - Jolly Cheeks Music - BMI
I looked for trouble and I found it son,
Straight down the barrel of a lawman's gun.
I'd try to run but I don't think I can,
You make one move and you're a dead man, friend.
Ain't livin' long like this,
Can't live at all like this, can I baby?
He slipped the handcuffs on behind my back,
Then left me freezin' on a steel rail rack.
Can't sleep at all in the jailhouse baby,
Ain't livin' long like this.
Grew up in Houston on the wayside drive,
Son of a car hop in some all nite dive.
Dad drove a stock car to an early death,
All I remember was a drunk man's breathe.
Ain't livin' long like this,
Can't live at all like this, can I baby?
We know the story how the wheel goes 'round,
Don't let 'em take you to the man downtown,
They got 'em all in the jailhouse baby.
Ain't livin' long like this,
Can't live at all like this, can I baby? Ah take it!
{Erik - Solo}
I live for Angel, she's a road house queen,
Makes Texas Ruby look like Sandra Dee.
I want to love her but I don't know how,
I'm at the bottom of a jailhouse now.
Ain't livin' long like this,
Can't live at all like this, can I baby?
You know the story 'bout the jailhouse rock,
Go on and do it, but just don't get caught.
They got 'em all in the jailhouse baby.
Oh, ain't livin' long like this.
Oh no!