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FCE 28260
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FCE 28260

FCE 28260 is a 5-alpha-reductase inhibitor drug with antiandrogenic activity, which was developed for the treatment of benign prostatic hyperplasia and androgenic (or androgenetic) alopecia in the 1990s. Its current status is unknown.

In a 1996 study, FCE 28260 inhibited rat and human 5-alpha-reductase with half maximal inhibitory concentrations (IC₅₀) of 15 and 16 nM, respectively, while finasteride had values of 30 and 52 nM.

References

1 2 Giudici, D.; Briatico, G.; Cominato, C.; Zaccheo, T.; Iehlè, C.; Nesi, M.; Panzeri, A.; Di Salle, E. (1996). "FCE 28260, a new 5 alpha-reductase inhibitor: In vitro and in vivo effects". The Journal of Steroid Biochemistry and Molecular Biology 58 (3): 299–305. doi:10.1016/0960-0760(96)00040-4. PMID 8836165.

↑ EP 0782582, Salle Enrico Di, Marcella Nesi, Achille Panzeri, "Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide", published 1997-07-09 .

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/FCE_28260

FCE

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FireChaser Express, an upcoming roller coaster at Dollywood;

FCE 28260, an inhibitor of 5 alpha-reductase;

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Free Church of England, an Anglican church which separated from the established Church of England in 1844;

Full Course Equivalent at Universities in Canada;

Full Credit Equivalent;

This page contains text from Wikipedia, the Free Encyclopedia - https://wn.com/FCE

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